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Pregnant women got vitamin D from govt – NONE achieved Vitamin D sufficiency – May 2017

The Effects of Vitamin D Supplementation during Pregnancy and Maternal Vitamin D Levels on Neonatal Vitamin D Levels and Birth Parameters.

J Matern Fetal Neonatal Med. 2017 May 5:1-16. doi: 10.1080/14767058.2017.1326897. [Epub ahead of print]

VitaminDWiki Comment

Publisher wants $54 for the PDF
Suspect that the Turkish govt provided only 400 IU for the pregnant women
Reminder - World Health Oeganization still recommends ZERO vitamin D while pregnant (as of May 2017)
Healthy pregnancies need lots of vitamin D has the following summary
Most were taking 2,000 to 7,000 IU daily for >50% of pregnancy
   Click on hyperlinks for details

Problem
Vit. D
Reduces
Evidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits
RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

Kılıcaslan AÖ1, Kutlu R2, Kilinc I3, Ozberk DI2.
1 Karatay Fetih Family Health Center , Konya , Turkey.
2 Necmettin Erbakan University, Meram Medicine Faculty, Dept. of Family Medicine , Konya , Turkey.
3 Necmettin Erbakan University, Meram Medicine Faculty, Dept. of Medical Biochemistry , Konya , Turkey.

OBJECTIVE:
The current study aimed to measure the levels of vitamin 25(OH)D in pregnant women and in the umbilical cord blood of newborns and to evaluate the association of vitamin D levels with birth parameters.

METHODS:
This cross-sectional analytic investigation was performed in 100 pregnant women at term and in 100 newborns born to these mothers. Plasma vitamin D level was measured and birth parameters of the babies were recorded.

RESULTS:
Mean vitamin D levels in pregnant women and cord blood were 11.39±6.24 ng/ml and 8.00± 4.95ng/ml, respectively. Vitamin D levels were found to be higher in the women who had received vitamin D support during pregnancy (p < 0.001).

  • Height (p = 0.004),
  • head circumference (p = 0.003), and
  • chest circumference (p = 0.005)

of newborns born to mothers who had received vitamin D support were higher compared to non-receivers. Maternal vitamin D deficiency (<10ng/ml) and insufficiency (10-30 ng/ml) was detected in 53.0% and 47.0% of the cases, respectively.
None of the women had sufficient levels of vitamin D.

CONCLUSION:
This study established that vitamin D levels were low in maternal and cord blood in spite of the administration program of Ministry of Health in pregnant women. The importance of vitamin D supplementation should be explained to the pregnant women in each visits.

PMID: 28475394 DOI: 10.1080/14767058.2017.1326897