Effects of Vitamin D Supplementation on Body Composition and Metabolic Risk Factors in Men: A Randomized Controlled Trial
Nutrients 2019, 11(8), 1894; https://doi.org/10.3390/nu11081894
Better than Daily
Obesity is associated with low Vitamin D (and treated by D as well) – Aug 2019 has:
Fast weight loss by Obese Adults: Summary of the data as of Sept 2019
1) 50,000 IU Vitamin D weekly for at least 6 months
If gut problems, should use a gut-friendly form of vitamin D
2) Add calorie restriction diet and light exercise after ~2 months*
* Vitamin D levels must be above 30ng/ml to help with weight loss
* Start losing weight 2 months sooner if take a 50,000 IU daily for a week
3) More weight loss if also add Magnesium or cofactors
30% Improved Vitamin D response with Magnesium - a Vitamin D Cofactor
Note: Magnesium reduces weight loss by itself as well
20% improved vitamin D response if also add Omega-3 a Vitamin D Cofactor
Note: Omega-3 reduces weight loss by itself as well
4) More weight loss if also improve activation of Vitamin D Receptor
Vitamin D Receptor activator: 0-30% improved Vitamin D response
Obesity 1.5 X more likely if poor Vitamin D Receptor – meta-analysis Nov 2019
Update Dec 2019 - Dr. Greger plant-based eating (not diet) for both weight loss and health.
His book does not mention Vitamin D nor Adenovirus
Items in both categories Obesity and Intervention – non daily are listed here:
- Obese women had larger response to oral v.s. injected Vitamin D – Jan 2024
- 20,000 IU of Vitamin D weekly gave many benefits – RCT Aug 2019
- Obese lost 3X more weight with Vitamin D - July 2018
- Severely Obese not helped much by 50,000 IU of vitamin D weekly for 8 weeks – RCT June 2019
- Obese responded to weekly vitamin D better than non-obese – RCT March 2018
- Daily, monthly Vitamin D had similar great benefits, more than 6 months needed – RCT Dec 2018
- Obese lost more weight on diet if added 50,000 IU of vitamin D weekly – many RCTs
- Response by obese to weekly 50,000 IU of Vitamin D – May 2018
- Waist size reduced 3 cm by Vitamin D in those with Metabolic Syndrome – Jan 2017
- 5,000 IU daily or 50,000 IU Vitamin D weekly repleted many dark skinned adolescents – RCT Dec 2015
- 50,000 IU vitamin D 1-3 times per week helped obese patients in rehab. – May 2013
Download the PDF from VitaminDWiki
by Elisabeth Lerchbaum 1,*,Christian Trummer 1,Verena Theiler-Schwetz 1,Martina Kollmann 2,Monika Wölfler 2,Stefan Pilz 1 andBarbara Obermayer-Pietsch 1
- 1 Division of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
- 2 Division of Obstetrics, Department of Obstetrics and Gynecology, Medical University of Graz, Auenbruggerplatz 14/1, 8036 Graz, Austria
Vitamin D might play a role in metabolic processes and obesity. We therefore examined vitamin D effects on metabolic markers and obesity in a randomized controlled trial (RCT). This is a post-hoc analysis of the Graz Vitamin D&TT-RCT, a single-center, double-blind, randomized placebo-controlled trial. We included 200 healthy men with serum 25-hydroxyvitamin D (25(OH) D) levels <75 nmol/L.
Subjects received 20,000 IU of vitamin D3/week (n = 100) or placebo (n = 100) for 12 weeks.
Outcome measures were metabolic markers, anthropometric measures, and body composition assessed by Dual-energy X-ray absorptiometry. One-hundred and ninety-two men completed the study. We found a significant treatment effect on
- fasting glucose/fasting insulin ratio (−5.3 (−10.4 to −0.2), p = 0.040),
whereas we observed no significant effect on the remaining outcome parameters.
In subgroup analyses of men with baseline 25(OH)D levels <50 nmol/L (n = 80), we found a significant effect on
- waist circumference (1.6 (0.3 to 2.9) cm, p = 0.012),
- waist-to-hip ratio (0.019 (0.002 to 0.036), p = 0.031),
- total body fat (0.029 (0.004 to 0.055) %, p = 0.026), and
- android fat (1.18 (0.11 to 2.26) %, p = 0.010).
In middle-aged healthy men, vitamin D treatment had a negative effect on insulin sensitivity.
In vitamin D deficient men, vitamin D has an unfavorable effect on central obesity and body composition.
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