Clinical improvement following vitamin D3 supplementation in Autism Spectrum Disorder.
Nutr Neurosci. 2017 Jun;20(5):284-290. doi: 10.1080/1028415X.2015.1123847. Epub 2016 Jan 18.
Feng J1, Shan L1, Du L1, Wang B1, Li H1, Wang W1, Wang T1, Dong H1, Yue X1, Xu Z2, Staal WG3, Jia F1,4,5.
ABCD
Social
Self Help
Not as much benefit if > 3 year
- Perhaps need higher dose if more weight?
Autism category in VitaminDWiki starts with
Autism category has - see also Overview Autism and vitamin D, Autoimmune , Cognitive, ADHD
Interesting Autistic studies
Autism associated with low Vitamin D
- Most Autism Risk factors are associated with low vitamin D - March 2014
- Rickets – 26 percent had autism: no rickets, no autism (both associated with low vitamin D) – June 2015
- Autistics have half of the response to Vitamin D – RCT Oct 2018
- Vitamin D fights autism - trying to figure out how and why – May 2022
Autism treated by Vitamin D
- Autism risk is reduced by Vitamin D – early pregnancy or chlldhood – Umbrella review – July 2024
- Autism treated by Vitamin D (monthly injection of 150,000 IU) – June 2017
- Autism decreased in 8 out of 10 children supplemented with vitamin D – April 2015
Autism reduced by vitamins before and during pregnancy
- Autism reduced 24% for each 4 ng more Vitamin D while pregnant ( ADHD 12%) – Feb 2024
- Low maternal Vitamin D results in larger portion of brain associated with autism – Jan 2020
- Autism risk reduced 2X by prenatal vitamins (Vitamin D or Folic) – Feb 2019
- Autism 3X more likely after closely spaced pregnancy vs 3 year apart– Jan 2011
- Low Vitamin D decreases fertility and increases subsequent autism, ADHD, etc – Feb 2018
- Women who had supplemented with any vitamins were 6 X less likely to have autistic offspring – Jan 2018
- Autism rate in siblings reduced 4X by vitamin D: 5,000 IU during pregnancy, 1,000 IU to infants – Feb 2016
Autism and Vitamin D Receptor (not enough Vit D gets to the cells)
This list is automatically updated
- More than 30% of Autistics also have ADHD - Nov 2024
- Autism treated by an activator of the Vitamin D Receptor: supforaphane - March 2024
- Autism may be synergistically treated by Vitamin D and probiotics – July 2022
- Autism 2X to 3X more likely if poor Vitamin D Receptor – June 2020
- A good Vitamin D Receptor (or perhaps more vitamin D) protects against lead during pregnancy
- Autism much more likely if poor Vitamin D Receptor – many studies
Autism - other risk factors
- Autistic symptoms reduced by Vitamin D and or Omega-3 – RCT March 2019
- Autism risk increased if infant had antibiotics (2X), acetaminophen (3X), or no vitamin D drops (1.5X) – June 2018
- 20 X more Parkinson's and 100X more Autism with GMO soy in China
- Note >100X increase in Autism while having GMO soy in the US
- Fewer neurons in males born from COVID-19 vaccinated mothers (rats) - Jan 2024
- Vaccinations resulted in increased office visits for children 16 months later - Nov 2020
- Does a vaccine increase the risk of Autism – March 2019
- Autism 2.75 X more likely in Hib vaccines containing Mercury – May 2018
- Vaccinated children had more chronic diseases - Sept 2018
- Autism and ADHD type disorders were 14X more likely in survey of extreme preterm vaccinated infants - April 2017
Dr. Cannell on Autism and Vitamin D in VitaminDWiki
- Autism treated by Vitamin D (80 – 120 ng) – Cannell update May 2018
- Autism Causes, Prevention and Treatment: Vitamin D Deficiency etc. – Book April 2015 Cannell
- Autism cured in a child with Vitamin D, Dr. Cannell comments and cofactor recommendations – March 2015
- Autism and Vitamin D - Dr. Cannell in Life Extension Mag - Jan 2014
- Autism treated by Vitamin D: Dr. Cannell - video June 2013
- includes his list of 27 reasons to associate Vitamin D with Autism in 2013
- Many autistic children are getting some Vitamin D, Omega-3, probiotics, etc. – Aug 2019
- Autistic symptoms reduced by Vitamin D and or Omega-3 – RCT March 2019
- Omega-3 probably can decrease Autism and ADHD – March 2019
- Autism treated in one person by Omega-3 plus Vitamin D – Dec 2018
- Autism problems reduced by Vitamin D, Omega-3 – RCT Oct 2018
- ADHD, Autism, Early Psychosis and Omega-3 – review Dec 2017
- Autism risks include chemicals, deficiency of vitamin D, Omega-3 – mini-review April 2016
This study used 3 monthly injections of 150,000 IU (no vary with child weight nor Vitamin D Level)
- Autism risk factors – many are associated with low vitamin D – meta-meta-analysis March 2017
- Vitamin D and autism - treat: 300 IU per kg per day, prevent: during pregnancy 5,000 IU – Feb 2017
- Autism 4 times more likely if low vitamin D during first trimester – Oct 2016
- Note - Most mothers-to-be who do supplement with Vitamin D do not get a good level until 2nd trimester
- Starting with loading doses gets a good level in weeks instead of months
- Autism and Vitamin D massive review – latitude, season, migration, VitD levels and intervention – April 2016
- Injection category listing has
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Injection works well, but is not requiredDownload the PDF from Sci-Hub via VitaminDWiki
OBJECTIVE:
High prevalence of vitamin D deficiency was previously reported in children with Autism Spectrum Disorder (ASD), but little is known about the efficacy of vitamin D3 treatment in ASD, although data from pilot studies seem promising. We hypothesized that serum vitamin D levels are reduced in ASD and correlate with the severity of disease. Also, we hypothesized that vitamin D3 treatment may be beneficial for a considerable portion of children with ASD.METHODS:
In total, 215 children with ASD and 285 healthy control children were recruited in our study. Thirty seven of 215 ASD children received vitamin D3 treatment. The Autism Behaviour Checklist (ABC) and the Childhood Autism Rating Scale (CARS) were used to assess autism symptoms. High-performance liquid chromatography was used to assess the serum 25-hydroxyvitamin D [25(OH) D] level. Evaluations of ABC, CARS, and serum 25(OH) D levels were performed before and after 3 months of treatment.RESULTS:
Serum levels of 25(OH) D were significantly lower in ASD children than typically developing children. Levels of serum 25(OH) D were negatively correlated with ABC total scores and language subscale scores. After vitamin D3 supplementation, symptom scores were significantly reduced on the CARS and ABC. In addition, the data also suggest that treatment effects were more pronounced in younger children with ASD.CONCLUSION:
Vitamin D deficiency might contribute to the aetiology of ASD. Supplementation of vitamin D3, which is a safe and cost-effective form of treatment, may significantly improve the outcome of some children with ASD, especially younger children (identifier ChiCTR-CCC-13004498).CLINICAL TRIAL REGISTRATION:
The trial 'Association of Polymorphisms of Vitamin D Metabolism-Related Genes With Autism and the Treatment of Autism with Vitamin D' has been registered at www.chictr.org/cn/proj/show.aspx? proj=6135 (identifier ChiCTR-CCC-13004498).PMID: 26783092 DOI: 10.1080/1028415X.2015.1123847
Autism treated by Vitamin D (monthly injection of 150,000 IU) – June 2017Printer Friendly Follow this page for updates7112 visitors, last modified 22 Dec, 2019, This page is in the following categories (# of items in each category)Attached files
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