Fibromyalgia pain substantially reduced by weekly Vitamin D (50,000 IU) – June 2018

Vitamin D Supplementation Seems to Improve Fibromyalgia Symptoms: Preliminary Results.

Isr Med Assoc J. 2018 Jun;20(6):379-381. PMID: 29911760
de Carvalho JF, da Rocha Araújo FAG, da Mota LMA, Aires RB, de Araujo RP.

VitaminDWiki

Visual analog scale scores (out ot 100)
90 Before
30 After

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VitaminDWiki Pain pages with FIBROMYALGIA in title

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Items found: 20
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Fibromyalgia pain, fatigue, etc. reduced by 50,000 IU of Vitamin D for 12 weeks – Sept 2023 04 Oct, 2023
Vitamin D at CureTogether: Fibromyalgia, MS, Psoriasis, etc - Dec 2013 11 Jul, 2023
Overview Fibromyalgia or Chronic Fatigue and vitamin D 11 Jul, 2023
Fibromyalgia Syndrome correlated with poor Vitamin D Receptor (less D to cells) in a small study – July 2022 24 Aug, 2022
Fibromyalgia and Musculoskeletal Pain treated by raised Vitamin D levels – July 2022 23 Jul, 2022
Fibromyalgia treated with Vitamin D (50,000 IU weekly for 3 months) – 2016, 2017, 2018, 2019 19 Oct, 2019
Fibromyalgia severity associated with serotonin but not Vitamin D (almost all were insufficient) – May 2019 27 May, 2019
Fibromyalgia pain substantially reduced by weekly Vitamin D (50,000 IU) – June 2018 23 Jun, 2018
Fibromyalgia associated with lower Vitamin D – meta-analysis Oct 2017 10 Feb, 2018
Fibromyalgia benefits from transdermal magnesium chloride – Sept 2015 09 Aug, 2017
Fibromyalgia helped by Vitamin D – still not sure how much, and why - June 2016 31 Dec, 2016
Fibromyalgia development 1.9 X more likely if low vitamin D – Jan 2016 20 Jan, 2016
Fibromyalgia pain reduced with vitamin D intervention that achieved 30-48 ng – RCT Feb 2014 05 Nov, 2015
High dose vitamin reduced pain of fibromyalgia, osteoarthritis, and rheumatoid arthritis - July 2015 11 Jul, 2015
Overlap between Fibromyalgia and other Chronic Pains – 2012 11 Jan, 2015
Fibromyalgia pain with trazodone reduced by 50 percent with weekly 50,000 IU of vitamin D – RCT Nov 2014 22 Nov, 2014
7100 IU vitamin D (50,000 weekly) significantly reduced fibromyalgia – 2009 20 Jan, 2014
Literature review of Fibromyalgia and vitamin D – Sept 2011 18 Dec, 2013
Fibromyalgia patients with low vitamin D have more pain – Dec 2013 18 Dec, 2013
No rise in vitamin D levels of fibromyalgia patients in the summer – Sept 2013 08 Sep, 2013

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BACKGROUND:
Vitamin D deficiency and insufficiency have been reported in fibromyalgia. However, to the best of our knowledge, only one study has evaluated the role of 25-hydroxyvitamin D [25(OH)D] supplementation on fibromyalgia symptoms.

OBJECTIVES:
To analyze the effects of 3 months of 25(OH)D supplementation on symptoms of fibromyalgia.

METHODS:
This study included 11 female patient. Demographic and clinical data, tender points, visual analog scale results, and pre- and post-serum levels of 25(OH)D supplementation were analyzed. The levels of 25(OH)D were measured by a radioimmunologic test.

RESULTS:
Patients with fibromyalgia diagnosis and 25(OH)D values ≤ 30 ng/ml were recruited to receive 50,000 IU of oral vitamin D once every week for 3 months. The disease was diagnosed based on the American College of Rheumatology criteria. The median age of all patients was 48.5 (28-67) years and 63.4% were Caucasian. Disease duration varied from 1-10 years. The 25(OH)D levels increased significantly after 3 months, 18.4 (15.5-25.8) ng/ml vs. 33.8 (28-58) ng/ml, P = 0.01. Interestingly, an improvement of visual analog scale scores was observed at 3 months, 90 (0-100) vs. 30 (0-80), P = 0.002.
Eight patients (72.2%) responded that they experienced a very significant improvement in symptoms. In addition, a trend for reduction of the number of tender points was observed after 3 months, 17 (11-18) vs. 10 (0-18), P = 0.07.

CONCLUSIONS:
The 25(OH)D levels and disease symptoms in patients with fibromyalgia and vitamin D deficiency/insufficiency seem to improve with vitamin D supplementation.

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