Table of contents
- Vitamin D Status and Risk of All-Cause and Cause-Specific Mortality in a Large Cohort: Results From the UK Biobank
- VitaminDWiki - Mortality and vitamin D – great chart
- VitaminDWiki - Mortality contains
- Mortality and Virus
59 studies - 38 Google Scholar citations of this study as of Aug 2022
- VitaminDWiki - VitaminDWiki mortality charts
Vitamin D Status and Risk of All-Cause and Cause-Specific Mortality in a Large Cohort: Results From the UK Biobank
J Clin Endocrinol Metab . 2020 Oct 1;105(10):dgaa432. doi: 10.1210/clinem/dgaa432.
Xikang Fan 1 , Jiayu Wang 1 , Mingyang Song 2 3 4 , Edward L Giovannucci 2 3 5 , Hongxia Ma 1 6 7 , Guangfu Jin 1 6 7 , Zhibin Hu 1 6 7 , Hongbing Shen 1 7 , Dong Hang 1 7
Context: Although an inverse association between vitamin D status and mortality has been reported in observational studies, the precise association shape and optimal vitamin D status remain undetermined.Objective: To investigate the association between vitamin D status and risk of all-cause and cause-specific mortality and estimate optimal serum 25-hydroxyvitamin D [25(OH)D] concentrations.
Design: Prospective cohort study.
Setting: UK Biobank.
Participants: 365,530 participants who had serum 25(OH)D measurements and no history of cardiovascular disease (CVD), cancer, or diabetes at baseline (2006-2010).
Main outcome measures: All-cause and cause-specific mortality.
Results: During a median follow-up of 8.9 (interquartile range: 8.3-9.5) years, 10,175 deaths occurred, including 1,841 (18.1%) due to CVD and 5,737 (56.4%) due to cancer. The multivariate analyses revealed nonlinear inverse associations, with a decrease in mortality risk appearing to level off at 60 nmol/L of 25(OH)D for all-cause and CVD deaths and at 45 nmol/L for cancer deaths.
Compared to participants with 25(OH)D concentrations below the cutoffs, those with higher concentrations had a- 17% lower risk for all-cause mortality (hazard ratio [HR]: 0.83, 95% confidence interval [CI]: 0.79-0.86), (24 ng)
- 23% lower risk for CVD mortality (HR: 0.77, 95% CI: 0.68-0.86), (24 ng)
- 11% lower risk for cancer mortality (HR: 0.89, 95% CI: 0.84-0.95).(18 ng)
Conclusions: Higher 25(OH)D concentrations are nonlinearly associated with lower risk of all-cause, CVD, and cancer mortality. The thresholds of 45 to 60 nmol/L might represent an intervention target to reduce the overall risk of premature death, which needs further confirmation in large clinical trials.
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VitaminDWiki - Mortality and vitamin D – great chart
VitaminDWiki - Mortality contains
People die sooner if they have low vitamin D
click on image for details- More vitamin D means fewer deaths – many studies
- Much more likely to live longer if higher vitamin D – 27,000 seniors Feb 2017
- 2,000 IU of Vitamin D daily to German Seniors would save 30,000 lives a year – March 2021
- Dr. Grant on vitamin D and mortality in VitaminDWiki
- Top 10 causes of death - low vitamin D is associated with every cause - Nov 2018
- Taking vitamin D extends life - 56 trials with 100,000 people - Dr. Greger video July 2016
- Much more likely to live longer if higher vitamin D – 27,000 seniors Feb 2017
- Low Vitamin D is associated with dying sooner (70 studies) – meta-analysis Jan 2019
- 4.8 X more likely to die within 28 days of ICU if low Vitamin D - Jan 2024
- Chance of dying in hospital cut in half by just 10 ng higher level of Vitamin D – April 2016
- Senior women having low vitamin D were 2X more likely to die - Sept 2023
- Risk of death after bone fracture was 6.6 X higher if less than 10 ng of vitamin D – June 2017
320 articles in Mortality category
Mortality and Virus
59 studies This list is automatically updated
- 15.3 X fewer COVID deaths in those getting Vitamin D injections in ICU – RCT July 2024
- COVID and Vitamin D: 2X more likely to die if low, 2X more likely to survive if supplement – umbrella meta-analysis April 2024
- Moderna report: their COVID vax caused "only" 17,751 deaths - April 2024
- COVID infection (without hospitalization) – 1.7X more likely to die in 6 months if low Vitamin D – March 2024
- Vaccines increased your risk of dying of COVID in NZ - official data - Feb 2024
- 3X increase in unspecified causes of Death (Canada 2019-2022) - Dec 2023
- Deaths after vaccination - also reported in Japan - Dec 2023
- Excess deaths after COVID vaccination - 17 countries - Sept 2023
- Excess Deaths in Australia jumped up in 2022– preprint Feb 2023
- Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
- Number needed to vaccinate to prevent 1 Omicron death: 30,000 for age 60-70 - Sept 2022
- COVID survival in Europe in 2020 best predicted by population-level Vitamin D (of 13 variables) – July 2022
- Elderly who had been in COVID ICU were 4X more likely to die if low vitamin D – Nov 2022
- More COVID mortality if less than 20 ng of Vitamin D (Mexico) – May 2022
- 15,000,000 excess deaths in 2 years - May 2022
- COVID death 5.2X more likely if Vitamin D deficient – May 2022
- 29 X more likely to die of COVID if less than 20 ng of Vitamin D - March 2022
- Giving Vitamin D reduced COVID Mortality– Review of 11 studies – March 2022
- 18 million excess global deaths in past 2 years: COVID plus collateral damage - Lancet March 2022
- COVID severity and death more likely if low vitamin D (Egypt this time) - March 2022
- US nursing homes are epicenters for COVID deaths (200,000) - Feb 2022
- Ivermectin taken before COVID decreased death rate by 68 percent (3,000 with Ivermectin vs 3,000 without) - Dec 24, 2021
- Increase in non-COVID deaths (ages 18-64) in Indiana, India, etc. - Jan 5, 2022
- Only 35,000 died in US of COVID who previously had been healthy
- COVID-19 mortality extrapolates to zero at 50 ng of vitamin D – 18th Meta-analysis Sept 2021
- COVID-19 patients getting 300,000 IU of Vitamin D were 5X less likely to die – Sept 2021
- Predict 2X more likely to die of COVID-19 if vitamin D Deficient (Iran 2020) – Sept 2021
- COVID-19 mortality not associated with Vitamin D (everyone had very low levels) -Sept 2021
- COVID-19 mortality for Blacks is 5X that for whites in 2 LA Hospitals - July 2021
- COVID-19 mortality was associated with vitamin D deficiency of 47 countries – July 2021
- Similar death rate for Vaccination and COVID-19 study and video – June 24, 2021
- COVID-19 death in hospital 5X more likely if low vs high vitamin D – preprint June 2021
- COVID-19 deaths 1.7X more likely if low vitamin D (even after “adjusting” for low D health problems) – May 2021
- COVID-19 deaths 1.5X less likely if more than 40 ng of vitamin D – US VA – April 2021
- Vitamin D supplementation and high levels reduce COVID-19 deaths in elderly – Review April 17, 2021
- Less COVID-19 infection, mortality in countries with higher Vitamin D (Asia in this case) – May 2021
- COVID-19 was the third-leading cause of death in the US, especially in those with dark skins - April 1, 2021
- Risk of COVID-19 death was 4.9 X higher if very low vitamin D – March 31, 2021
- COVID-19 mortality 2X higher if low Vitamin D (Mexican hospital, preprint) - March 2021
- All COVID-19 patients had low vitamin D, the lowest were more likely to die – Feb 18, 2021
- 2.7 fewer COVID-19 hospital deaths in those having more than 30 ng of vitamin D – Mayo Jan 9, 2021
- Worse COVID-19 patients got 400,000 IU of vitamin D, deaths cut in half – Jan 14, 2021
- Iranians with COVID-19 were 2.3 X more likely to die if low vitamin D – Jan 2021
- Poor COVID-19 prognosis was 6 X more likely if low vitamin D – Jan 21, 2021
- Less than 10 dollars of Vitamin D per COVID-19 life saved in Myanmar - Jan 2021
- 2.8 X fewer COVID-19 nursing home deaths if add 10,000 IU Vitamin D daily for a week (small observation)- Jan 2021
- Italian nursing home COVID-19 – 4X less likely to die if taking Vitamin D– Dec 22, 2020
- Shift workers 2X more likely to get COVID-19 (low Vitamin D) - Dec 2020
- Those getting high dose vitamin D were 7 X less likely to die of COVID-19 - Dec 11, 2020
- COVID-19 male mortality increased 3.9 X if low vitamin D – observation Nov 25, 2020
38 Google Scholar citations of this study as of Aug 2022
- Circulating 25-hydroxy-vitamin D and the risk of cardiovascular diseases. Systematic review and meta-analysis of prospective cohort studies- November 2021 https://doi.org/10.1016/j.numecd.2021.09.003
- Calcifediol (25OH Vitamin D3) Deficiency: A Risk Factor from Early to Old Age - March 2022 https://doi.org/10.3390/nu14061168 FREE PDF
- Serum 25-hydroxyvitamin D, frailty, and mortality among the Chinese oldest old: Results from the CLHLS study- August 2021 https://doi.org/10.1016/j.numecd.2021.05.033
- Gene-Environment Interactions in Vitamin D Status and Sun Exposure: A Systematic Review with Recommendations for Future Research -June 2022 https://doi.org/10.3390/nu14132735 - FREE PDF
Citations that included COVID in their title
- Vitamin D3 for reducing mortality from cancer and other outcomes before, during and beyond the COVID-19 pandemic: A plea for harvesting low-hanging fruit - July 2022 https://doi.org/10.1002/cac2.12328 FREE PDF
- Vitamin D and COVID-19 —Revisited - July 2022 https://doi.org/10.1111/joim.13536 FREE PDF
- Vitamin D and COVID-19: evidence and recommendations for supplementation December 2020 https://doi.org/10.1098/rsos.201912 FREE PDF
- Low serum 25-hydroxyvitamin D (25OHD) levels in patients hospitalized with COVID-19 are associated with greater disease severity - . 2020 Nov; https://doi.org/10.1111/cen.14310.FREE PDF
- New Roles for Vitamin D Superagonists: From COVID to Cancer - March 2021 https://doi.org/10.3389/fendo.2021.644298 FREE PDF
VitaminDWiki - VitaminDWiki mortality charts
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