Vitamin D Status May Affect Resilience and Recovery from Mild Traumatic Brain Injury in Military Personnel
Laurel M Wentz wentzl@ecu.edu
Department of Nutrition Science, East Carolina University, USA
Department of Nutrition Science, RW-333 Rivers Building, Mail Stop 505, East Carolina University, Greenville, NC 27858-4353, USA, Tel: 2523289414;
Received: March 19, 2014; Accepted: May 08, 2014; Published: May 09, 2014
Experiencing mild traumatic brain injury (mTBI) may lead to chronic post- concussive symptoms, increasing the risk for post-traumatic stress disorder (PTSD) and suicide. Vitamin D deficiency is associated with cognitive decline, depression, and potentially PTSD through its relationship to testosterone production. Furthermore, vitamin D deficiency elevates systematic inflammation, meaning that poor vitamin D status at the time of blast may prolong inflammatory response to mTBI and exacerbate post-concussive symptoms. Since widespread vitamin D deficiency is observed across the U.S. population, poor vitamin D status is expected in service members. Given the high risk for mTBI in service members and suboptimal vitamin D levels observed in this population, treatment of vitamin D deficiency and elucidation of its mechanism in mTBI resilience and recovery merits exploration. Evidence in this review investigates possible protection of achieving optimal vitamin D levels for mTBI resiliency and recovery through its influence on inflammatory and hormonal biomarkers. Despite interest in using vitamin D as treatment for TBI, no human trials have tested the role of vitamin D in mTBI resiliency or recovery, nor have data been prospectively collected on the prevalence of vitamin D deficiency in service members. The neuroprotective effects of vitamin D warrant further investigation into the role of vitamin D in mTBI management.
Download the PDF from VitaminDWiki.
Nurse thesis on Vitamin D and TBI - 2016
Download the PDF from VitaminDWiki.
fails to mention this study nor those by Matthews
Does have nice appendix of Vitamin D pro and anti-inflammation and bibliography
See also VitaminDWiki
- 5 Traumatic brain injuries resulted in 2.8 X increased risk of dementia – April 2018
- Vitamin D and Glutamine reduced Trauma Center deaths by half – Matthews March 2017
- Traumatic brain injury treated by Vitamin D Progesterone Omega-3 and glutamine – May 2013
- Huge increase in Vitamin D supplementation in the US military (2005-13) – Oct 2016
- Military and Vitamin D - many studies co-authored by Wentz
- Magnesium may be an important way to treat brain trauma
- Spinal cord problems more likely if TBI if little Omega-3 in diet – June 2013
- High-fructose diet slows recovery from brain injury - TBI, rats - Oct 2015
- US Army learning about benefits of vitamin D to trauma – Matthews Dec 2013
- Vitamin D and Glutamine resulted in 2.6X reduction in trauma center mortality rate – Dec 2014
- Vitamin D aided progesterone in reducing traumatic brain injury – RCT Dec 2012
- Search VitaminDWiki for TBI OR "Traumatic Brain Injury" 303 items as of Aug 2017
- Concussions (traumatic brain injury) getting big press coverage, vitamin D might be both a cause and a solution
- Omega-3 prevents PTSD and some mood disorders - Aug 2015