Monthly 120,000 IU of Vitamin D while breastfeeding was good – RCT Jan 2022

Even better: 50,000 IU of vitamin D every 12 days starting a month before pregnancy

Effect of Maternal Supplementation with Two Different Doses of Vitamin D During Lactation on Vitamin D Status, Anthropometry and Bone Mass of Infants: A Randomized Controlled Trial

Indian Pediatr. 2022 Jan 9;S09747559160039
Rekha Ramot 1, Swati Yadav 2, S K Vishnoi 2, Pramod Sharma 2, Rajesh Khadgawat 1, Rakesh Jora 3

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Background: There is a high prevalence of vitamin D deficiency (VDD) in exclusively breast-fed infants in the absence of appropriate vitamin D supplementation.

Objective: To evaluate the efficacy of two doses of maternal vitamin D supplementation on vitamin D levels of mother-infant pairs and to assess its effect on growth parameters(weight, length and head circumference) and bone mass of infants.

Study design: Randomized controlled trial.

Participants: Lactating mother-infant pairs (n=220).

Intervention: Maternal oral vitamin D supplementation in two doses (group 1: 120 000 IU/month and group 2: 12000 IU/month for 12 months.

Main-outcomes: Maternal and infant serum 25OHD levels, and infant's growth and bone mass.

Results: There was high prevalence of VDD at baseline in mothers (94%) as well as infants (98.5%) which was reduced to 43.1% in (mothers) and 46.5% in infants after 12 months. Significantly higher median (IQR) serum 25OHD levels (ng/mL) were observed among mothers in group 1 compared to group 2 [46 (17-159) vs 18 (6-64); P<0.01] and in infants [36.5 (15-160) vs 17 (7-32); P<0.01]. No significant association was observed between growth parameters or bone mass and serum 25OHD levels of mother or infant between the two groups. Four mothers (3.6%) and two infants (1.8%) in group I had serum 25OHD>100 ng/mL, but without hypercalciuria or hypercalcemia.

Conclusion: Bolus vitamin D supplementation in the dose of 1,20,000IU/month was more efficacious in improving maternal and infant vitamin D status at 12 months, as compared to 12,000 IU/month.
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39+ VitaminDWiki pages have BREASTFED or BREASTFEEDING in the title

This list is automatically updated

Items found: 39
Title Modified
Breastfeeding Vitamin D loading dose of 300,000 IU is OK - UK govt. Dec 2023 04 Jan, 2024
Vitamin D levels of breastfeeding mothers and infants in 3 cities – Feb 2015 29 Aug, 2023
Breastfeeding and Vitamin D - many studies 29 Aug, 2023
Breastfed Infants need more than an daily average of 800 IU of Vitamin D – RCT June 2022 21 Jun, 2022
Need at least 6,000 IU of Vitamin D daily during pregnancy and breastfeeding (Wagner) – meta-analysis March 2022 15 Apr, 2022
Monthly 120,000 IU of Vitamin D while breastfeeding was good – RCT Jan 2022 11 Jan, 2022
Breastfeeding is almost always associated with infant vitamin D deficiency – Dec 2021 14 Dec, 2021
Need at least 6,000 IU daily while breastfeeding to eliminate Vitamin D deficiency – meta-analysis Oct 2021 01 Nov, 2021
400 IU of Vitamin D helped breastfed infants, need more – RCT Sept 2021 01 Sep, 2021
36X more likely for an infant to be low vitamin D if exclusively breastfed (Hong Kong) – March 2021 26 Jul, 2021
6,400 IU of Vitamin D is safe and effective during breastfeeding – RCT Dec, 2020 16 Dec, 2020
Breastfeeding a child without adding vitamin D increases risk of many food allergies (egg whites in this case) – Jan 2020 12 Jan, 2020
Omega-3 during pregnancy and breastfeeding is recommended – May 2019 23 May, 2019
Maternal vitamin D deficiency can trigger rickets in breastfed infants – review March 2013 03 Feb, 2019
Biochemical rickets non-existent if breastfeeding mother got 600,000 IU of vitamin D (3 dollars) – RCT Dec 2017 03 Mar, 2018
Breastfed infant bones not helped by 800 IU of Vitamin D (not enough) – RCT Dec 2017 12 Dec, 2017
Extended breastfeeding cut in half the risk of Multiple Sclerosis – July 2017 28 Nov, 2017
Mother got 100,000 IU of vitamin D monthly, breastfeeding infant got a little – RCT Aug 2016 13 Sep, 2017
Breastfeeding mothers and Vitamin D: supplement only themselves usually, 4 out of 10 used monthly rather than daily – Jan 2017 05 Aug, 2017
Severe childhood dental problems 2.4 X more likely if breastfed for more than two years (low vitamin D) – June 2017 02 Jul, 2017
Vitamin D required for breastfed infants – daily or monthly, infant or mother – Jan 2017 20 May, 2017
Breastfeeding mother getting 6400 IU of Vitamin D is similar to infant getting 400 IU – RCT Sept 2015 25 Jan, 2017
Breastfed infants 6 times more likely to deficient in Vitamin D and Iron – Aug 2015 20 Jun, 2016
Breastfed infants: 90 percent had less than 20 ng of vitamin D, formula-fed: 15 percent – May 2013 20 Jun, 2016
Breastfed child needs even more vitamin D supplementation after 1 year – Feb 2016 28 Feb, 2016
Breastfeeding exclusively may not be best strategy for bone health (if not add vitamin D) – Feb 2016 16 Feb, 2016
NutraIngredients.com Breastfeeding exclusively may not be best strategy for bone health (if not add vitamin D) - Feb 2016 16 Feb, 2016
Breastfed infants may get enough vitamin D (provided mom gets 6400 IU) - Oct 2015 07 Oct, 2015
400 IU vitamin D for breastfed - American Association of Pediatrics - Feb 2012 23 Sep, 2014
16% of exclusively breastfed infants so low on vitamin D that they had rickets – June 2010 28 Aug, 2014
Breastfed without vitamin D supplements – a problem for NZ infants Jan 2013 28 Aug, 2014
Breastfeeding with daily or monthly doses of vitamin D virtually the same – RCT Dec 2013 01 Feb, 2014
Breastfeeding with daily or monthly doses of vitamin D fairly similar – Dec 2013 14 Dec, 2013
6400 IU vitamin D is effective during breastfeeding – Oct 2010 14 Dec, 2013
Breastfed Infants in Iowa got very little vitamin D, especially if winter or dark skin – July 2013 05 Jul, 2013
Only about 10 percent of breastfed infants get even the minimum recommended vitamin D – April 2010 26 Jun, 2013
Breastfed infants in Germany with 250 IU of vitamin D got to 56ng – Sept 2010 04 Sep, 2012
Hypothesis – vitamin D links breastfeeding difficulties and depression – July 2011 19 Jul, 2011
Vitamin D for breastfeeding - Hollis medical slides 2010 No value for &#039;modification_date_major&#039;

VitaminDWiki - Pregnancy category contains:

920 items in Pregnancy category

 - see also

VitaminDWiki - Healthy pregnancies need lots of vitamin D

Most were taking 2,000 to 7,000 IU daily for >50% of pregnancy
   Click on hyperlinks for details

Problem
Vit. D
Reduces		Evidence
0. Chance of not conceiving3.4 times Observe
1. Miscarriage 2.5 times Observe
2. Pre-eclampsia 3.6 timesRCT
3. Gestational Diabetes 3 times RCT
4. Good 2nd trimester sleep quality 3.5 times Observe
5. Premature birth 2 times RCT
6. C-section - unplanned 1.6 timesObserve
     Stillbirth - OMEGA-3 4 timesRCT - Omega-3
7. Depression AFTER pregnancy 1.4 times RCT
8. Small for Gestational Age 1.6 times meta-analysis
9. Infant height, weight, head size
     within normal limits		 RCT
10. Childhood Wheezing 1.3 times RCT
11. Additional child is Autistic 4 times Intervention
12.Young adult Multiple Sclerosis 1.9 timesObserve
13. Preeclampsia in young adult 3.5 timesRCT
14. Good motor skills @ age 31.4 times Observe
15. Childhood Mite allergy 5 times RCT
16. Childhood Respiratory Tract visits 2.5 times RCT

RCT = Randomized Controlled Trial

VitaminDWiki - Weekly, Monthly Vitamin D are typically better than daily - many studies

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