Once-a-Week Administration of 25-Hydroxy Vitamin D3 to Sustain Elevated Steady-State Pharmacokinetic Blood Concentration
United States Patent Application 20200281947 Kind Code:A1
Inventors: Deluca, Hector F. (Deerfield, WI, US). Plum, Lori A. (Arena, WI, US), Clagett-dame, Margaret (Deerfield, WI, US)
An oral dosage form comprising a single dose of 25-hydroxy-vitamin D3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days and a pharmaceutically suitable oral carrier system, wherein subsequent single doses at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed. A method of elevating and sustaining the blood level concentration of 25-hydroxy-vitamin D3 in a human in need thereof comprising
- orally administering or
- parenterally administering by injection or infusion,
at least once every 7 days, a single dose of 25-hydroxy-vitamin D3 sufficient to elevate the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml for at least 7 days, wherein the single doses orally administered at least every 7 days are sufficient to sustain the serum level in a human to a concentration in the range of 30 ng/ml to 200 ng/ml at steady-state pharmacokinetics is disclosed. The human in need thereof may be a human deficient in vitamin D having a serum level concentration of 25-hydroxy-vitamin D3 less than 30 ng/ml.
Patent Text
Download the Patent PDF image from VitaminDWiki
Getting Vitamin D into your body has the following chart
Who said vitamin D could not be patented International Patents 2018
International Patents
Multiple Sclerosis with 10,000 IU of Vitamin D + Biotin + Folate + Vitamin B12 + Vitamin C = etc. by Valery Lipenko, Nov 2018
(RU0002665969) PCOS Sept 2018 6,000 IU, 45 nanogram
WO2018136490) June 2018 Common Cold probiotic, vitamin C and vitamin D
(RU0002660341) PMS in girls July 2018 4,000 IU if a few poor genes, otherwise 2.000 IU
(US20180169034) TRANSDERMAL DELIVERY FORMULATION June 2018, Transdermal patch
(EP3320952) TREATING MULTIPLE SCLEROSIS May 2018, WISCONSIN ALUMNI RES FOUND, DELUCA
COGNITIVE HEALTH AND MEMORY Jan 2018, 1,000-5000 IU vitamin D + Omega-3
Prevent Hair loss from Chemotherapy Jan 2018
Vitamin D Patents have so far been made for
- PCOS, Breast and many other cancers, Obesity, Fall prevention, Stroke and other Cardiovascular,
- Immune system, wounds and reduce scars, Kidney disease, Diabetes, improve fertility,
- decrease pregnancy problems, SAD, multiple sclerosis (2),chemoprevention of cancer,
- accelerate fracture healing, metabolic syndrome, periodontitis, gingivitis, endometreosis,
- hair loss due to Chemotherapy, asthma, allergy, PMS in girls, ADHD
A patent is a good indication that Vitamin D
can treat/prevent a health problem
A patent is one of the 22 Criteria to associate a health problem with low vitamin D
See also
Who said vitamin D could not be patented
Vitamin D fortification patents have earned Univ. of Wisconsin 300 million dollars– 2016