Vitamin D Status in Patients With Severe Sepsis (ViDISS)
Patients will be given 400,000 IU of vitamin D3 within 24 hours of severe sepsis onset followed by weekly doses of 25,000 IU
Principal Investigator: Sadeq A Quraishi, MD Massachusetts General Hospital
- Sepsis is both prevented and treated by Vitamin D - many studies VitaminDWiki – which includes
200,000 and 400,000 IU of vitamin D reduced septic shock, length of stay - RCT June 2015
Two Meta-analyses of ICU and Vitamin D - April and May 2017
Sepsis injection of 300,000 IU of vitamin D helped in a small RCT Feb 2017 - Sepsis is 13 X more likely if poor Vitamin D Receptor – April 2017
- Sepsis: 4 fewer days in ICU if add Omega-3 – meta-analysis of 12 RCT – June 2017
- See also: Vitamin D is needed before most surgeries – many studies and RCTs
Promising Vitamin D Clinical Trials - 2017 contains the following
- Monthly 60,000 IU of Vitamin D did not reduce mortality (too infrequent)- Feb 2022monthly) will reduce mortality – results due 2024
- Probably Fractures of the Tibia can be healed with 100,000 IU of vitamin D weekly – RCT 2023
- Severe sepsis may be prevented by 400,000 IU of vitamin D – RCT 2023
- Decalcify Aortic Valve – 3 year trial with 1 mg of Vitamin K and 5,000 IU of Vitamin D – 2021
- Multiple Sclerosis stem cell treatment (HSCT) probably not benefit from 200,000 IU of vitamin D – RCT 2020
- Delay onset of Multiple Sclerosis with 100,000 IU of vitamin D every two weeks – RCT 2020
- Vitamin D taken daily (4,000 IU) vs weekly (50,000 IU) – RCT 2019
- Critically ill children – randomized clinical trial to give single doses of up to 400,000 IU of vitamin D – 2019
- Each page includes links to similar studies/trials
- The year is shown as 1 year after trial starts, note sometimes publication does not occur until 4 years later.
- These clinical trials were selected as being likely to show good results by VitaminDWiki in 2017.
- If an item is of interest. you should consider taking Vitamin D and perhaps other supplements such as Magnesium, Omega-3, and Vitamin K rather than waiting for the results of the clinical trial to be published, or waiting several decades for your doctor to incorporate the results into his practice
See also VitaminDWiki
- Vitamin D home fortification- don't wait 100 years for your govt
- Vitamin D and Rickets consensus took 80 years – how long till consensuses on 30 other health problems – Feb 2016
- A balanced diet is no longer enough – supplements needed - VitaminDWiki Oct 2012
- VITAMIN D: Public Shouldn’t Wait For Doctors To Usher In New “Golden Era” Of Preventive Medicine
- Vitamin D trials underway are unlikely to be useful – Jan 2015 10 reasons, such as too small of dose, too short of time, dose size not vary with weight, . .
- Intervention - Vitamin D category listing has
824 items along with related searches - Vitamin D intervention -100 active clinical trials as of May 2018
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