Many Clinical Trials now using 10,000 IU of vitamin D to TREAT MS

Australia Feb 2012,~hs~~hs~~hs~ Germany Feb 2012,~hs~~hs~~hs~ July 2011, ~hs~~hs~~hs~ May 2011 injection,~hs~~hs~~hs~April 2010

MS and Vitamin D

• Dec 2010 20,000 IU vitamin D and MS – less fatigue and relapse
• Overview MS and vitamin D both PREVENT and TREAT: 17 Clinical trials for MS, Being used for MS more than any other disease,
  3 books with sections on MS, Found to be far better than FDA drug for MS. Many MS websites are very pro vitamin D
• 3X less Multiple Sclerosis with enough vitamin D US Veterans Administration

Be careful when increasing vitamin D

• Some chemos are amplified by vitamin D which can be deadly if chemo dose is not reduced
• A few drugs have poor interactions with vitamin D
• Warning - must balance Calcium and Magnesium when greatly increasing Vitamin D has the following notional graph

• The following text is copied from the graph for translation
  • Probability of adverse reaction when increasing Vitamin D (rough guess)
  • Calcium too much
  • Magnesium: too little
  • Vitamin D in blood (nanograms/ml)

MS is in a vicious cycle with vitamin D:

Low vitamin D ==>MS ==> lower vitamin D ==> many more vitamin D deficiency diseases

CLICK HERE for more about deficiencies and vicious cycles

Exponential increase in Vitamin D publications

But - UV might be even better than Vitamin D

• MS 20X more correlated to UV than other variables – Jan 2011
• Lack of UV increased offspring MS - April 2010
• Increased sun and vitamin D both reduced MS risk – March 2011
• UV suppresses MS but vitamin D might not – March 2010

Can use both UV and Vitamin D (unless you are in a Vitamin D clinical trial)

• No – 10 minutes per day of sun-UVB is NOT enough
  long exposure time needed if you are elderly or obese or have dark skine
  extremely long exposure time if more if you fit into more than one of the above categories
• How you can optimize vitamin D from the sun
• Overview Suntans melanoma and vitamin D If you use a tanning bed be sure that it has a natural ratio of UVA to UVB
• All items in category UV and Vitamin D 161 items Feb 2012
• Overview UV and vitamin D
• UV produces more than vitamin D – Aug 2011
• Opinion: sun better than UV better than vitamin D

Vitamin D PREVENTS many diseases and TREATS some (such as MS)

Many clinical trials have proven the power of vitamin D to treat 35 diseases, including MS

Notice that the 10,000 IU needed for MS = the amount on the following chart

CLICK HERE for world-wide Vitamin D recommendations: both US and nanograms

This graph shows that in 2010 that vitamin D levels > 40 ng PREVENTED Multiple Sclerosis

CLICK HERE for larger image and more charts of disease incidence

FACT: At least some MS is associated with a gene variant

FACT: People with MS need higher levels of vitamin D to treat the symptoms

SPECULATION: Those people with the gene variant need higher levels of vitamin D in the blood to prevent/treat MS

• Mutation of Vitamin D gene is strongly tied to MS – Dec 2011
• MS and vitamin D may be related by HLA gene – March 2010 has a link to a 2009 video
• MS associated with 29 new and 23 previously known gene variants – Aug 2011
• MS due to low level of vitamin D may be due to a specific gene – July 2010 CYP27B1
• MS and vitamin D may be related by HLA gene – March 2010 (MS Society UK - not VitaminDWiki)
• Far more likely to get MS if blood relatives have had MS - MS Org.

See also VitaminDWiki

• How you might double the benefit of your vitamin D
• No – 10 minutes per day of sun-UVB is NOT enough
• Many reasons why vitamin D deficiency has become epidemic in past 30-40 years
• Free, instant test to see if you are very vitamin D deficient - it is not quantitative
• All items in Vitamin D Blog
• Home Page
• List of categories of vitamin D information - with # of items in each
• Low cost and many forms of vitamin D costs about 25 cents per week.
• Vitamin D 101
• Overview Rare Allergic reaction to vitamin D
  test yourself with low dose first, to be sure you are not the 1 in 300 who get an allergic reaction to vitamin D
• MS relapse reduction: low-cost vitamin D or high cost new drug blog post