Cystic Fibrosis is associated with low Magnesium, supplementation would probably help -review 2016

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Magnesium in cystic fibrosis--Systematic review of the literature

Pediatr Pulmonol. 2016 Feb;51(2):196-202 doi: 10.1002/ppul.23356
Maristella Santi 1 , Gregorio P Milani 2 , Giacomo D Simonetti 1 3 , Emilio F Fossali 2 , Mario G Bianchetti 1 , Sebastiano A G Lava 1 3

Background: The metabolism of sodium, potassium, and chloride and the acid-base balance are sometimes altered in cystic fibrosis. Textbooks and reviews only marginally address the homeostasis of magnesium in cystic fibrosis.

Methods: We performed a search of the Medical Subject Headings terms (cystic fibrosis OR mucoviscidosis) AND (magnesium OR hypomagnes[a]emia) in the US National Library of Medicine and Excerpta Medica databases.

Results: We identified 25 reports dealing with magnesium and cystic fibrosis. The results of the review may be summarized as follows. First, hypomagnesemia affects more than half of the cystic fibrosis patients with advanced disease; second, magnesemia, which is normally age-independent, relevantly decreases with age in cystic fibrosis; third, aminoglycoside antimicrobials frequently induce both acute and chronic renal magnesium-wasting; fourth, sweat magnesium concentration was normal in cystic fibrosis patients; fifth, limited data suggest the existence of an impaired intestinal magnesium balance. Finally, stimulating observations suggest that magnesium supplements might achieve an improvement in respiratory muscle strength and mucolytic activity of both recombinant and endogenous deoxyribonuclease.

Conclusions: The first comprehensive review of the literature confirms that, despite being one of the most prevalent minerals in the body, the importance of magnesium in cystic fibrosis is largely overlooked. In these patients, hypomagnesemia should be sought once a year. Furthermore, the potential of supplementation with this cation deserves more attention.
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VitaminDWiki - 3 studies in both categories Cystic Fibrosis and Magnesium

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VitaminDWiki - Magnesium and Vitamin D contains

365 items in category, see also

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Mg and Vitamin D

• Intracellular Magnesium and Vitamin D - a few studies
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• Why Vitamin D is Useless without This Critical Nutrient (Magnesium) - Jan 2019
• 500 mg of Magnesium for 8 weeks increased Vitamin D by 4 ng – July 2020
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• Magnesium and Vitamin D – recent deficiencies, needed, synergistic - good overview 2017
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• Magnesium and Vitamin D - similar, different and synergistic

Magnesium topics gathered on a page

• Vitamin D, Omega-3, and Magnesium are synergistic - many studies
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• Low Magnesium associated with severe COVID – many studies
• Calcium to Magnesium Ratio - many studies
• Magnesium Role in Health and Longevity - many studies
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• Vitamin D and Magnesium need each other - many studies
• Pregnancy helped by Magnesium - many studies

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VitaminDwiki – Cystic Fibrosis category has 52 items along with related searches