- High level of vitamin D/UV reduces the risk of many gut problems
- Many gut problems result in less absorption of Vitamin D & Magnesium . . .
Not restoring Vitamin D levels increases the risk of many other diseases - Increasing Vitamin D reduces many inflammations - incude those of the gut
- Several companies make gut-friendly forms of vitamin D
- There are
208 items in the Gut category in VitaminDWiki
(more GUT information below)Learn how Vitamin D is essential for good health
Is 50ng enough? How to restore levels quickly VitaminDWiki interview and transcript - Lahore Jan 2022
Watch a 5 minute video "Does Less Sun Mean more Disease?"
Browse for other Health Problems and D in left column or here
see also Supplementing and More in the menu at the top of every page
If you have a disease associated with low Vit D take Vit D
Raising your Vit D levels will substantially prevent other low-Vit D health problems
Proof that Vitamin D Works Getting Vitamin D into your body
Books and Videos274 Diseases that may be related via low vitamin D
Reasons for low response to vitamin D Why are doctors reluctant
Cancer studies include: Breast259 Colon 145 Lung 55 Prostate 103 Pancreatic 58 Skin 121
Colds and flu Dark Skin468 Diabetes 553 Obesity 442 Pregnancy 922 Seniors 431
COVID-19 treated by Vitamin D - studies, reports, videosTable of contents
- Gut Summary
- See VitaminDWiki (other than Crohn's)
- 9 gut problems - in order of prevelance - Perplexity AI June 2024
- 4 gut problems are associated with low vitamin D levels - Perplexity AI June 2024
- 87% of eating disorders got worse with COVID-19 - Aug 2020
- Many gut diseases will do better with gut-friendly forms of Vitamin D
- See also web
- Review of IBD and Vitamin D (generally < 1,000 IU) - Feb 2014
- SBI can help Colitis - Aug 2022
- IBS vs IBD
- Colon Diseases
- Celiac
- Celiac assocated with both low vitamin D and poor Vitamin D Receptor - meta-analsys - Feb 2023
- Celiac disease is the most common genetic disease in Europe.
- Celiac Disease is similar to Crohn's Disease in that both decrease vitamin D which can be absorbed in the gut
- Does Gluten-Free Diet Protect Children with Celiac Disease from Low Bone Density? - Aug 2014
- 8+ VitaminDWiki pages with CELIAC in title
- Crohn's
Gut Summary
- Gut problems result in reduced absorption of Vitamin D, Magnesium, etc.
- Celiac disease has a strong genetic component.
- Most, but not all, people with celiac disease have a gene variant.
- An adequate level vitamin D seems to decrease the probability of getting celiac disease.
- Celiac disease causes poor absorption of nutrients such as vitamin D.
- Bringing the blood level of vitamin D back to normal in patients with celiac disease decreases symptoms.
- The prevalence of celiac disease, not just its diagnosis, has increased 4X in the past 30 years, similar to the increase in Vitamin D deficiency.
- Review in Nov 2013 found that Vitamin D helped
Many intervention clinical trials with vitamin D for Gut problems (101 trials listed as of Sept 2019) - All items in category gut and vitamin D
208 items - There are many ways to get vitamin D to people with poor guts
There is a low-cost form of vitamin D designed for use with gut problems
See VitaminDWiki (other than Crohn's)
- "Ulcerative Colitis" OR UC 1420 items Feb 2021
- "celiac disease" OR CD 2030 items Jan 2019
- IBS or IBD or IRRITABLE BOWEL in title of 37 VitaminDWiki pages as of July 2021
- diverticulitis 21 items as of Feb 2018
- IBD in Canadian children increasing 7% per year - Nov 2016
- 88 percent of Intestinal failures had both low vitamin D and low bone density – Feb 2013
- Vitamin D might reduce military costs for UC and CD – June 2011
- All items in category gut and vitamin D
208 items - Gut doctors becoming aware of importance of vitamin D – May 2012
- Many items in the journal Gut and the Journal of Crohn's and Colitis Spring 2012
- Ulcerative colitis associated with both low Vitamin D and poor Vitamin D Receptors – Oct 2016
- Ulcerative Colitis relapse 25 percent more likely if vitamin D level is lower than 35 ng – June 2016
- Antibiotics and Vitamin D are associated with many of the same diseases
- Inflammatory bowel diseases treated with vitamin D – Review May 2014
- IBD more likely in areas with low UV ( and thus low vitamin D) – June 2014
- Inflammatory bowel diseases are helped by vitamin D – commissioned review Nov 2013
- Gut problems associated with low vitamin D – invited review Dec 2015
- Irritable Bowel Syndrome - can it be treated by 3000 IU of vitamin D - RCT Feb 2014
- Better response to Inflammatory Bowel Disease drug if more than 30 ng of vitamin D – March 2014
- Gut microbiome massively changed by weekly vitamin D – July 2015
- Vitamin D injection is far better than oral for diabetics (poor gut) – RCT March 2017
- Inflammatory diseases: review of vitamin D, with many tables – May 2014 which has a summary table
9 gut problems - in order of prevelance - Perplexity AI June 2024
- Irritable Bowel Syndrome (IBS) - Affects 12% of the US population, making it the most common digestive disorder.
- Gastroesophageal Reflux Disease (GERD) - Along with IBS, GERD is noted as one of the digestive disorders seeing a noticeable rise in incidence.
- Constipation - Chronic constipation affects 15-30% of Canadians and is especially common in young children and the elderly.
Inflammatory Bowel Disease (IBD) - IBD, which includes Crohn's disease and ulcerative colitis, had an estimated 4.9 million prevalent cases globally in 2019.
- Gastritis - Inflammation of the stomach lining, commonly caused by H. pylori infection, NSAIDs, or alcohol.
- Peptic Ulcers - Often associated with gastritis and caused by H. pylori infection or NSAID use.
- Pancreatitis - Had an estimated 2.41 million prevalent cases globally in 2019.
- Appendicitis - Had an estimated 0.67 million prevalent cases globally in 2019.
- Paralytic Ileus and Intestinal Obstruction - Had an estimated 0.55 million prevalent cases globally in 2019.
4 gut problems are associated with low vitamin D levels - Perplexity AI June 2024
- Inflammatory Bowel Disease (IBD), including Crohn's Disease and Ulcerative Colitis:
Vitamin D deficiency is more common among those with IBD.
Lower vitamin D levels are associated with higher disease activity and severity in Crohn's disease.
Vitamin D deficiency may be implicated in the etiology and severity of IBD.
Individuals with higher serum vitamin D have a lower incidence of IBD, particularly Crohn's disease. - Constipation:
A study found that patients with chronic functional constipation and intestinal motility disorders had lower vitamin D levels compared to healthy controls.
Low vitamin D levels were significantly correlated with constipation symptoms and impaired quality of life in these patients. - Diarrhea:
Low vitamin D levels are associated with an increased risk of rotaviral diarrhea in children under 5 years old.
A study found lower vitamin D levels in children with acute bacterial diarrhea compared to healthy children. - General Gastrointestinal Inflammation:
Vitamin D plays a role in maintaining gastrointestinal barrier integrity, regulating gut microbiota, and modulating inflammatory immune responses, which are important in preventing and ameliorating gut inflammation.
References
87% of eating disorders got worse with COVID-19 - Aug 2020
Exploring the impact of the COVID-19 pandemic and UK lockdown on individuals with experience of eating disorders
UK study, FREE PDF
Many gut diseases will do better with gut-friendly forms of Vitamin D
Gut-friendly, Sublingual, injection, topical, UV, sunshineGetting Vitamin D into your body has the following chart
Getting Vitamin D into your body also has the following
If poorly functioning gut
Bio-D-Mulsion Forte – especially made for those with poorly functioning guts, or perhaps lacking gallbladder
Sublingual – goes directly into the bloodstream
Fat-soluble Vitamins go thru the slow lymph system
you can make your own sublingual by dissolving Vitamin D in water or use nano form
Oil: 1 drop typically contains 400 IU, 1,000 IU, or 4,000 IU, typically not taste good
Topical – goes directly into the bloodstream. Put oil on your skin, Use Aloe vera cream with Vitamin D, or make your own
Vaginal – goes directly into the bloodstream. Prescription-only?
Bio-Tech might be useful – it is also water-soluble
Vitamin D sprayed inside cheeks (buccal spray) - several studies
and, those people with malabsorption problems had a larger response to spray
Inject Vitamin D quarterly into muscle, into vein, or perhaps into body cavity if quickly needed
Nanoparticles could be used to increase vitamin D getting to the gut – Oct 2015
Poor guts need different forms of vitamin D has the following
Guesses of Vitamin D response if poor gutBio Form Speed Duration 10 Injection ($$$)
or Calcidiol or CalcitriolD - Slow
C -FastLong 10 Sun/UVB Slow Long 10 Topical
(skin patch/cream, vagina)Slow
Fast nanoNormal 9 Nanoemulsion -mucosal
perhaps activates VDRFast Normal 9? Inhaled (future) Fast Normal 8 Bio-D-Mulsion Forte Normal Normal 6 Water soluble (Bio-Tech) Normal Normal 4 Sublingual/spray
(some goes into gut)Fast Normal 3 Coconut oil based Slow Normal 2 Food (salmon etc.) Slow Normal 2 Olive oil based (majority) Slow Normal 10= best bioavailable, 0 = worst, guesses have a range of +-2
Speed: Fast ~2-6 hours, Slow ~10-30 hours
Duration: Long ~3-6 months, Normal = ~2 monthsSee also web
- https://ckarchive.com/b/k0umh6hd8dmdx?ck_subscriber_id=1050764595IBS extensive review at Examine.com March 2023
- 65% of GIRD in children elminated by removing cows milk from diet - even thou they were not "allergic to the milk
- Michael Greger July 2019 text and 5 minute video
- https://clinicaltrials.gov/ct2/show/NCT04225819?sfpd_s=12%2F30%2F2019&sfpd_d=14Clinical trial starting in 2020 giving Vitamin D (10,000 IU) for 14 weeks
- Doomed to fail. People with poor guts need gut-friendly form of Vitamin D
- Vitamin D Insufficiency Linked to Irritable Bowel Syndrome and Sports Injuries Mercola Feb 2018
"About 75 percent of people with IBS have insufficient levels of vitamin D, and about 70 percent report improvement when taking vitamin D supplements" Reference: Jan 2018 $5 to rent the PDF - Vitamin D for Inflammatory Bowel Disease Dr. Greger’ Jan 2017
3 minute video looking at the scientific reasons to believe IBD is associated with low Vitamin D
Includes random controlled trials using increasing dose sizes - 5,000 IU treating most IBD very well - Why Everyone with Celiac Disease Desperately Needs Vitamin D SCD Lifestyle 2012
Vitamin D can stop your intestines from leaking, Vitamin D helps put the fire out - Coeliac Disease has increased 4X in the past 30 years in Clinical Education web UK
- Elderly had 2.5X as much Celiac as the rest of Finnish population
- seems reasonable - elderly have much less vitamin D since generate only 1/3 as much vitamin D from the same amount of sun
- African Americans get Celiac as well long forum discussion
- Search for Gut Clinical Trials with vitamin D INTERVENTION 103 trials listed as of Feb 2018
(gut OR bowel OR Gluten intolerance OR "Celiac Disease" or "Crohn's Disease" OR "Ulcerative Colitis" OR "Inflammatory Bowel Disease") with "vitamin d" intervention - Search for "Crohn's Disease" and vitamin d" intervention 26 trials as of Feb 2018
- IBS Self Help and Support Forum 142 items on vitamin D as of Nov 2016
- ACG clinical guidelines: diagnosis and management of celiac disease. AHRQ May 2013
Mentions Vitamin D and other nutrients in treatment section - Optimal vitamin D levels in Crohn's disease: a review Feb 2015
 Download the PDF from VitaminDWiki - Cannabis Superior To Drugs For Inflammatory Bowel Condition (Crohn's Disease) GreenMedInfo April 2015
RCT with 21 patients, Vitamin D not mentioned, but vitamin D appears to treat the disease, and not just the pain
 Download the PDF from VitaminDWiki - Study links increased dietary zinc intake to reduced risk of Crohn's May 2015
Result of questionaires of 200,000 people - corrected for changes due to Vitamin D, smoking, BMI, etc.
< 8 mg Zinc no change, 8-16 mg daily==> 30% reduction, > 16 mg daily ==> 48% reduction - Cut out FODMAPs, cut out IBS symptoms? Examine.com Dec 2016
FODMAP= "Fermentable, Oligo-saccharides, Di-saccharides, Mono-saccharides, and Polyols."
Less FODMAP in diet ==> less gas; review of a meta-analysis - Why Everyone with Celiac Disease Desperately Needs Vitamin D SCDLifestyle 2012
- Using Essential Oils to Heal the Gut GreenInfo Aug 2017
Nothing about Vitamin D. Oils for Leaky Gut, Irritable Bowel Syndrome, GERD, . . . - Gut Flora - has the following graphic
Review of IBD and Vitamin D (generally < 1,000 IU) - Feb 2014
Review of observational and intervention studies
 Download the PDF from VitaminDWiki
SBI can help Colitis - Aug 2022
SBI = Serum-Derived Bovine Immunoglobulin/Protein Isolate,
by Eugene Heyden
IBS vs IBD
Colon Diseases
Celiac
Celiac assocated with both low vitamin D and poor Vitamin D Receptor - meta-analsys - Feb 2023
A meta-analysis suggests the association of reduced serum level of vitamin D and T-allele of Fok1 (rs2228570) polymorphism in the vitamin D receptor gene with celiac disease
Front Nutr . 2023 Jan 19;9:996450. doi: 10.3389/fnut.2022.996450
Tanya Shree 1, Pratibha Banerjee 1, Sabyasachi Senapati 1Purpose: As an immune-modulator, vitamin D is known to regulate immune response and is implicated in disease pathogenesis. Celiac disease (CD) is a systemic autoimmune disease and susceptibility conferred by vitamin D metabolism is under investigation. Studies on the association of vitamin D metabolism and genetic polymorphisms are expected to explain CD pathogenesis. We performed a systematic review-based meta-analysis to investigate the 25(OH)D serum levels and susceptibility conferred by the genetic variants of VDR in CD.
Methods: Systematic review was conducted through a web-based literature search following stringent study inclusion-exclusion criteria. The Newcastle-Ottawa Scale and GRADE tools were used to assess the quality of evidence in studies and the study outcome. Cohen's κ value was estimated to access the reviewer's agreement. RevMan 5.4.1 was used to perform the meta-analyses. Weighted mean difference and Meta p-value was assessed for 25(OH)D serum levels. Meta-odds ratio and Z-test p-value were evaluated to estimate the allelic susceptibility of VDR variants.
Results: A total of 8 out of 12 studies were evaluated for "25(OH)D" serum level, while four studies were found eligible for SNPs (Bsm1, Apa1, Fok1, and Taq1) of VDR. Significantly higher levels [WMD = 5.49, p < 0.00001] of 25(OH)D were observed in healthy controls than in patients with CD. rs2228570-T (Fok1) [Meta-OR = 1.52, p = 0.02] was confirmed to be predisposing allele for CD.
Conclusion: Reduced serum level of 25(OH)D and association of Fok1 T-allele of VDR confirmed in this study plays a critical role in immunomodulation and maintaining barrier integrity, which is majorly implicated in CD.
 Download the PDF from VitaminDWiki
Celiac disease is the most common genetic disease in Europe.
In Italy about 1 in 250 people and in Ireland about 1 in 300 people have celiac disease.
from http://www.wrongdiagnosis.com/c/celiac_disease/prevalence.htm
Celiac Disease is similar to Crohn's Disease in that both decrease vitamin D which can be absorbed in the gut
Celiac Disease may be similar to Crohn's Disease on the following chart
Does Gluten-Free Diet Protect Children with Celiac Disease from Low Bone Density? - Aug 2014
 Download the PDF from VitaminDWiki.
They believe: CD ==> poor absorption ==> low vitamin D ==> low Bone Mineral Density
They conclude that if teen with CD has bone pain should have DXA test of BMD, then might consider giving vitamin D.
8+ VitaminDWiki pages with CELIAC in title
This list is automatically updated
Items found: 11
Crohn's
Crohn's reduced by plant-based diet - Dr. Greger
Crohn's reactions to yeast, milk, eggs - good video review of many studies (video with transcript)- Feb 2021
Is Nutritional Yeast Healthy for Everyone? Dr. GregerThe Best Diet for Crohn’s Disease Treatment Video with transcript April 2021
Vitamin D levels OK months before Crohn's, but were low only after Crohn's
Crohn's and Colitis infographic
39+ VitaminDWiki pages with CROHN in title
This list is automatically updated
Items found: 39
15 gut questions and answers – NYT Feb 2023
The Wild World Inside Your Gut
Questions- 1 How can I tell if my gut is healthy? And what are some warning signs that it isn’t?
- 2 How does my gut affect the rest of my body?
- 3 What are some simple things I can do to improve my gut health?
- 4 Are there any foods I should limit for the sake of my gut health?
- 5 I often feel heartburn after I eat. Why is that and what can I do to stop it?
- 6 Am I at risk for an ulcer if I am constantly stressed and eat a lot of spicy food?
- 7 What is ‘leaky gut syndrome’ and how do I know if I have it?
- 8 Can refined carbs like sugar or white flour cause an overgrowth of yeast in my gut?
- 9 Are antibiotics bad for my gut health? And if so, what can I do to prevent the damage?
- 10 I’ve seen a lot of ads for colon cleanses. What are they and should I do one?
- 11 So what should I do to take care of my colon?
- 12 What can the shape, type and frequency of my stool tell me about my health?
- 13 If I see identifiable foods in my stool, does that mean I have a food intolerance?
- 14 What actually works to prevent constipation?
- 15 If I use over-the-counter laxatives, will my gut build up a tolerance or become dependent on them?
Overview Gut and vitamin D106688 visitors, last modified 16 Jun, 2024, This page is in the following categories (# of items in each category)Attached files
ID Name Uploaded Size Downloads 19265 NYT Gut.pdf admin 22 Feb, 2023 120.09 Kb 310 19178 Celiac Vit D, VDR meta.pdf admin 07 Feb, 2023 1.31 Mb 317 10941 IBD vs IBS.jpg admin 01 Dec, 2018 29.38 Kb 9474 10469 Crohn's and Colitis.jpg admin 03 Sep, 2018 175.61 Kb 5980 9421 Colon Diseases.jpg admin 27 Feb, 2018 28.14 Kb 5975 7385 Optimal vitamin D levels in Crohn’s disease - a review.pdf admin 24 Nov, 2016 1.40 Mb 1691 5307 Cannabis Crohn's.pdf admin 14 Apr, 2015 465.15 Kb 2509 5212 1987.jpg admin 22 Mar, 2015 87.79 Kb 6808 5211 Poor D2 absorption if poor gut - 1987.pdf admin 22 Mar, 2015 1.29 Mb 2069 4125 CD and low vitamin D July 2014.pdf admin 10 Jul, 2014 593.50 Kb 2725 3618 IBS Vitamin D Council.jpg admin 15 Feb, 2014 477.02 Kb 11664 3604 IBD - Feb 2014.pdf admin 08 Feb, 2014 3.92 Mb 4307 2654 intestinal-microflora-gut-floria-health.jpg admin 26 Jun, 2013 37.90 Kb 12085 - Gut doctors becoming aware of importance of vitamin D – May 2012
- There are many ways to get vitamin D to people with poor guts