UV reduces cardiovascular and metabolic problems– Vitamin D plus Nitric oxide – Sept 2023

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Impact of ultraviolet radiation on cardiovascular and metabolic disorders: The role of nitric oxide and vitamin D

Photodermatol Photoimmunol Photomed. 2023 Sep 20. doi: 10.1111/phpp.12914
Qing-Ling Quan 1 2 3, Kyeong-No Yoon 1 2 3, Ji Su Lee 1 2 3, Eun Ju Kim 1 2 3, Dong Hun Lee 1 2 3

Proven benefits in mice

Background/purpose: Ultraviolet (UV) radiation has both harmful and beneficial effects on human skin and health. It causes skin damage, aging, and cancer; however, it is also a primary source of vitamin D. Additionally, UV radiation can impact energy metabolism and has protective effects on several cardiovascular and metabolic disorders in mice and humans. However, the mechanisms of UV protection against these diseases have not been clearly identified.

Methods: This review summarizes the systemic effects of UV radiation on hypertension and several metabolic diseases such as obesity, diabetes, and nonalcoholic fatty liver disease (NAFLD) in mice, and we also consider the mechanisms of action of the related regulators nitric oxide (NO) and vitamin D.

Results: UV exposure can lower blood pressure and prevent the development of cardiovascular diseases and metabolic disorders, such as

• metabolic syndrome,
• obesity, and
• type 2 diabetes,

primarily through mechanisms that depend on UV-induced NO.
UV radiation may also effectively delay the onset of type 1 diabetes through mechanisms that rely on UV-induced vitamin D. UV-induced NO and vitamin D play roles in preventing and slowing the progression of NAFLD.

Conclusion: UV exposure is a promising nonpharmacological intervention for cardiovascular and metabolic disorders. NO and vitamin D may play a crucial role in mediating these effects. However, further investigations are required to elucidate the exact mechanisms and determine the optimal dosage and exposure duration of UV radiation.
 Download the PDF from VitaminDWiki

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12+ VitaminDWiki pages with NITRIC OXIDE in the title

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VitaminDWiki – Noontime sun and D category:

Noontime sun and D has 331 items

see also
No – 10 minutes per day of sun-UVB is NOT enough
Vitamin D Myths - SUN
Optimize vitamin D from the sun
Overview Suntan, melanoma and vitamin D
Overview UV and vitamin D
50 ng of Vitamin D - 100 hours of noon sunbathing OR 3 dollars of Vit D
3.3 X more likely to be Vitamin D deficient if wear long-sleeves – Oct 2022
Sun and UV
Avoiding the sun may be as bad as smoking - many studies
Vitamin D from the sun without the heat (silver-coated plexiglass)
Opinion: sun better than UV better than vitamin D
Fewer cognitive problems if more sun or Vitamin D
Which Is Worse - Avoiding Sunlight or Vitamin D Deficiency – April 2019
Have We Gotten Sunscreen Totally Wrong - Jan 2019
People who get little noon-day sun must supplement with Vitamin D – systematic review June 2017
The Greatest Public Health Mistake of the 20th Century (sunscreen block Vitamin D) - 2017
Does Less Sun mean More Disease 5 minute video
340,000 US deaths annually due to insufficient sun (some due to low vitamin D) – July 2020
Health benefit of Sunlight is more than Vitamin D in the blood - many studies
5 Amazing Properties of Sunlight You've Never Heard About
Vitamin D and Sun conference – Germany June 2017

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VitaminDWiki - 5 studies in both categories Cardiovascular and UV

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VitaminDWiki - 3 studies in both categories Metabolic Syndrome and UV

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VitaminDWiki - 4 studies in both categories Obesity and UV

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VitaminDWiki - Sun is better than UV, which is better than Vitamin D

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VitaminDWiki - Health benefit of Sunlight is more than Vitamin D in the blood - many studies