Table of contents
- COVID-19 pandemic and vitamin D: rising trends in status and in daily amounts of vitamin D provided by supplements
- VitaminDWiki Virus pages with 50 ng in title (7 as of Aug 2022)
- VitaminDWiki pages with IRELAND in title (13 as of Aug 2022)
- VitaminDWiki – COVID-19 treated by Vitamin D - studies, reports, videos
COVID-19 pandemic and vitamin D: rising trends in status and in daily amounts of vitamin D provided by supplements
BMJOPEN http://dx.doi.org/10.1136/bmjopen-2021-059477
Malachi J McKenna1 malachi.mckenna at ucd.ie, Oonagh C Lyons2, Mary AT Flynn2, Rachel K Crowley1, Patrick J Twomey1, Mark T Kilbane1
Objectives Since the onset of the COVID-19 pandemic in 2020, there have been plausible suggestions about the need to augment vitamin D intake by supplementation in order to prevent SARS-CoV2 infection and reduce mortality. Some groups have advocated supplementation for all adults, but governmental agencies have advocated targeted supplementation. We sought to explore the effect of the COVID-19 pandemic on both vitamin D status and on the dose of new-to-market vitamin D supplements.
Setting University hospital, Dublin, Ireland.
Participants Laboratory-based samples of circulating 25-hydroxyvitamin D (25OHD) (n=100 505).
Primary and secondary outcome measures Primary outcomes: comparing yearly average 25OHD prior to the pandemic (April 2019 to March 2020) with during the pandemic (April 2020 to March 2021) and comparing the dose of new-to-market vitamin D supplements between 2017 and 2021 (n=2689). Secondary outcome: comparing prevalence of vitamin D deficiency and vitamin D excess during the two time periods.
Results The average yearly serum 25OHD measurement increased by 2.8 nmol/L (61.4, 95% CI 61.5 to 61.7 vs 58.6, 95% CI 58.4 to 58.9, p<0.001), which was almost threefold higher than two similar trend analyses that we conducted between 1993 and 2016. There was a lower prevalence of low 25OHD and a higher prevalence of high 25OHD. The dose of new-to-market vitamin D supplements was higher in the years 2020–2021 compared with the years 2017–2019 (p<0.001).
Conclusions We showed significant increases in serum 25OHD and in the dose of new-to-market vitamin D supplements. The frequency of low vitamin D status reduced indicating benefit, but the frequency of vitamin D excess increased indicating risk of harm. Rather than a blanket recommendation about vitamin D supplementation for all adults, we recommend a targeted approach of supplementation within current governmental guidelines to at-risk groups and cautioning consumers about adverse effects of high dose supplements on the market.
Download the PDF from VitaminDWiki
VitaminDWiki Virus pages with 50 ng in title (7 as of Aug 2022)
This list is automatically updated
VitaminDWiki pages with IRELAND in title (13 as of Aug 2022)
This list is automatically updated
VitaminDWiki – COVID-19 treated by Vitamin D - studies, reports, videos
As of March 31, 2024, the VitaminDWiki COVID page had: trial results, meta-analyses and reviews, Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, All 26 COVID risk factors are associated with low Vit D, Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID 166 COVID Clinical Trials using Vitamin D (Aug 2023) Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries