Depression and Type 2 Diabetes Mellitus: A Call to Explore the Common Cause Hypothesis
Briana Mezuk, PhD, Department of Epidemiology and Community Health, Virginia Commonwealth University School of Medicine, Richmond, VA (bmezuk@vcu.edu).
Archives of Internal Medicine Vol. 171 No. 11, June 13, 2011
(Short item with just the first 150 words of the full text)
I read the recent article by Pan and colleagues1 with great interest. Their findings using the Short-Form 36 Health Status Survey suggest that even mood disturbances that do not require clinical intervention are predictive of diabetes. This interpretation, combined with the counterintuitive finding that nonsevere depression was similarly, and potentially more strongly, associated with diabetes risk than severe depression reported in another recent article,2 begs the question(s):
- What is it about depressed mood, regardless of severity, that predicts diabetes?
- Is there some omitted confounder that could explain this finding?
The "Patient Perspective" that accompanied the recent article by Campayo and colleagues2 hints at a potential candidate: stress.
The woman described in this vignette experienced both a major life event—widowhood—and complicated bereavement prior to onset of diabetes.
Stressful life events are a well-documented cause of depression.3 Recent work on the physiologic consequences of stress (canonized in concepts such . . .
See Also VitaminDWiki
- All items in category Depression and Vitamin D
268 items - Overview Diabetes and vitamin D
- Depression 2X more common among diabetics, both associated with low vitamin D – 2014
Items in both categories Diabetes and Deproession are listed here:
- Water-soluble form of vitamins are needed for some health problems
- Depression more likely if low vitamin D (3.5 X prediabetic women in this case) – Oct 2022
- Depression reduced in Diabetics with 3 months of 4,000 IU of vitamin D – RCT July 2019
- Depression twice as common in Diabetics (both have low vitamin D) – Aug 2018
- Vitamin D treatment of diabetes (50,000 IU every 2 weeks) augmented by probiotic – RCT June 2018
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- ALL of the top 10 health problems of women are associated with low vitamin D
- Depression 2X more common among diabetics, both associated with low vitamin D – 2014
- 50,000 IU Vitamin D weekly Improves Mood, Lowers Blood Pressure in Type 2 Diabetics – Oct 2013
- Hypothesis non-severe depression and diabetes related by low vitamin D – June 2011
- Chicago Sun Times on vitamin D: Depression, chest pain, fibromyalgia, Holick, 3000 IU without test - May 2010
- Table of outcomes for seniors vs vitamin D level
Hypothesis non-severe depression and diabetes related by low vitamin D – June 2011Printer Friendly Follow this page for updates5395 visitors, last modified 10 Jul, 2019, This page is in the following categories (# of items in each category)