What is the rate of increased unplanned pregnancies due to weight loss drugs - Asked Perplexity AI May 2024
The rate of increased unplanned pregnancies due to weight loss drugs like Ozempic, Mounjaro, Wegovy, and Zepbound is not precisely quantified in the available sources. However, there is a notable trend of unexpected pregnancies among women using these medications, which has been widely reported in various media outlets and social media platforms.Several factors contribute to this phenomenon:
- Improved Fertility: Weight loss induced by these medications can correct hormonal imbalances, particularly in women with conditions like polycystic ovary syndrome (PCOS), thereby restoring regular ovulation and increasing the likelihood of pregnancy.
- Reduced Effectiveness of Birth Control: These drugs can slow gastric emptying, which may interfere with the absorption of oral contraceptives, making them less effective and increasing the risk of unplanned pregnancies.
- Anecdotal Reports: Numerous anecdotal reports and social media posts have highlighted cases of women becoming pregnant while on these medications, even when using birth control or having a history of infertility.
- Lack of Comprehensive Data: While there are many anecdotal reports, comprehensive data on the exact rate of increased unplanned pregnancies is lacking. Drug manufacturers and researchers are currently collecting data to better understand the safety and implications of these medications during pregnancy.
In summary, while there is a clear trend of increased unplanned pregnancies among women using weight loss drugs, the exact rate is not well-documented. The phenomenon is attributed to both improved fertility due to weight loss and the potential reduced effectiveness of oral contraceptives when taken with these medications.
17 references
VitaminDWiki – Vitamin D greatly improves Fertility
- Vitamin D is needed for human fertility – goal is 50 ng – Sept 2018
- In-vitro Fertilization costs at least 10,000 dollars, Vitamin D costs 5 dollars
- Infertile patients 1.7X more-likely to become pregnant if take Vitamin D – meta-analysis Feb 2023
- Live birth 1.7 X more likely after IVF if good level of vitamin D – meta-analysis Aug 2020
- If diagnosed infertile, more likely to have live birth if Vitamin D fortification – Feb 2020
- Preconception vitamin D is great - every extra 10 ng associated with 10 percent more likely to have live birth – Aug 2018
- Women with more than minimum vitamin D were 3.4 X more likely to achieve pregnancy and 1.6 X more likely to have live births – June 2017
- Assisted Reproduction – 5 studies concluded vitamin D repletion helps – Review March 2015
- Pregnancy success increased 30 percent if sunny (or vitamin D) one month earlier – June 2015
- IVF 4X more successful for white women with lots of vitamin D – many studies
Increased male Vitamin D increases fertility
- Birth rates doubled with Vitamin D - 300,000 for infertile men – RCT Nov 2017
- Higher vitamin D results in 22% fewer abnormal sperm (Mendelian analysis) – May 2024
- Conception was 3.7X more likely if the male had a good level of Vitamin D – July 2022
- Far better sperm in fertility clinic if more than 30 ng of Vitamin D - June 2022
- Fertility (sperm) associated with vitamin D – meta-analysis Sept 2019
- Infertility - 71 percent of the time of BOTH partners had less than 20 ng of Vitamin D – Aug 2017
- Male fertility 4 X higher if high Vitamin D – Nov 2015
- Vitamin D somewhat assists reproduction – both the mother and the father – May 2014
Decreased Fertility if decreased Vitamin D Receptor
- Unexplained infertility 4X more likely if poor vitamin D receptor – Dec 2020
- Male Infertility is associated with poor Vitamin D Receptor – July 2021