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CYP27B1


The CYP27B1 gene activates Vitamin D in the Kidney,    Skin,    Lungs,    Brain,   Eyes   Breasts   etc.
Poor CYP27B1 is assocated with COVID, Miscarriage,   Lupus,   Alz, Parkinson, MSA,   Rickets

CYtochrome P450 family 27 subfamily B member 1    = 25-Hydroxyvitamin D3 1-alpha-hydroxylase

What can be done if have a poor CYP27B1

  • Larger doses of Vitamin D
  • More Bio-available: Gut-friendly form, Topical form, taken with fatty meal, taken with evening meal
  • Additional sources: UV
  • Increase Vitamin D metabolism: additional Magnesium, Omega-3
    • All cytochrome P450 enzymes require Mg++ as a cofactor
  • Increase the amount of Vitamin D in the blood that gets to cells: increase activation of VDR

Vitamin D blood test misses CYP27B1 and other genes
in Visio for 2023

Here are all of the CYP27B1 articles

See also web

  • Gene therapy for CYB27B1extended the lives of mice with acute myeloid leukemia - compared to placebo
    • A novel vitamin D gene therapy for acute myeloid leukemia
    • Behind paywall DOI: 10.1016/j.tranon.2020.100869 Sept 2020
  • Higher risk of Atrial fibrilation of poor CYP27B1
    • Vitamin D Status in Patients with Atrial Fibrillation and Heart Failure - Is there a Link? - June 2021
    • Details are behind a paywall @ DOI: 10.7754/Clin.Lab.2020.200902

CYP27B1 Associations: Genetics 37, Vitamin D Receptor 33, Vit D Binding Protein 21, Cancer - Breast 4, Pregnancy 4, Vision 3 Cognitive 3, UV 3

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Summary of Associations

Associated category Associations
Genetics
40
Vitamin D Receptor
36
Vit D Binding Protein
22
Vision
3
Cancer - Breast
4
Kidney
3
Top news
3
Cognitive
3
Pregnancy
5
UV and Vitamin D
3

Results

40 pages in both categories: CYP27B1 + Genetics

Page Hits Categories Major change
Acupuncture of scalp activates Vitamin D genes CYP27a1, CYP27b1, and CYP24a (rats with strokes) – May 2024 8 Genetics , CYP27B1 23 May, 2024
Obesity is associated with 1 to 5 poor vitamin D genes (childhood obesity in the case) – July 2024 9 Obesity, Genetics , Infant-Child, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 16 May, 2024
Gestational Diabetes and Vitamin D - many studies Pregnancy, Genetics , Vitamin D Receptor, CYP27B1 10 Apr, 2024
Gestational Diabetes and Vitamin D - many studies Pregnancy, Genetics , Vitamin D Receptor, CYP27B1 10 Apr, 2024
Vitamin D and it’s related genes regulate the immune system – Aug 2023 903 Autoimmune, Immunity, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 13 Aug, 2023
12 Vitamin D genes (Most are not noticed by blood test) – Sept 2021 400 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 16 Jul, 2023
Cervical Cancer is prevented by Vitamin D, and treated if caught early (genes are important) – May 2023 439 Genetics , Cancer - Other, Vitamin D Receptor, CYP27B1 27 May, 2023
Response to Vitamin D - many studies 1480 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 07 Apr, 2023
Vitamin D genes vary with UVB in Europe, Africa, Asia – March 2020 373 UV and Vitamin D, Genetics , Middle East, Vitamin D in Europe, Vitamin D Receptor, Vit D Binding Protein, Orient, CYP27B1, Africa 06 Apr, 2023
Vitamin D genes may be more important than (25(OH)D) to orthopedics – Review Dec 2022 1943 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 08 Dec, 2022
Brain cells can probably activate Vitamin D without liver or kidney (at least in rats) – Sept 2017 3387 Genetics , Vit D Binding Protein, CYP27B1 25 Oct, 2022
Neuro problems (AD, PD, MSA) associated with poor vitamin D genes (CYP27A1, CYP27B1) – Sept 2022 1301 Parkinson, Genetics , Cognitive, CYP27B1 08 Sep, 2022
COVID virus alters the activation of 100 vitamin D related genes in the lung – April 2021 2209 Genetics , Vitamin D Receptor, Vit D Binding Protein, Virus, CYP27B1 16 Aug, 2022
An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022 1365 Vision, Genetics , Vitamin D Receptor, CYP27B1 24 Jul, 2022
Vitamin D genes – Review June 2022 2539 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 30 Jun, 2022
Vitamin D metabolism and genes as of Nov 2019 1494 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 13 Jun, 2022
Poor vision associated with poor Vitamin D or poor Vit. D genes – June 2022 1592 Vision, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 05 Jun, 2022
Vitamin D levels in cells, not blood, is important (IVF follicular fluid in this case) – Aug 2021 2296 Fertility and sperm, Genetics , Top news, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 27 Apr, 2022
Better handgrip strength if some good vitamin D genes (or if supplement) – April 2022 1431 Sports and Vitamin D, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 09 Apr, 2022
Does survival of the less fit mean less health (poor genes may be inherited) 3328 Genetics , Top news, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 15 Feb, 2022
Vitamin D Metabolite Profiling and genes (CYP24A1, CYP27B1)– Nov 2021 1336 Genetics , CYP27B1 08 Dec, 2021
Mucosal membranes (mouth, lungs, nose, intestines, etc) can activate Vitamin D – July 2020 3596 Breathing, Forms of Vitamin D, Genetics , Inflammation, Vitamin D Receptor, CYP27B1 14 Sep, 2020
Vitamin D genes are important, update – Sept 2020 2152 Genetics , Vitamin D Receptor, CYP27B1 12 Sep, 2020
Parathyroid increase with age associated with worsening Vitamin D genes – April 2020 3891 Seniors, Genetics , Thyroid and parathyroid, Vitamin D Receptor, CYP27B1 01 May, 2020
Glucocorticoid treatment reduces Vitamin D getting to cells via 3 or 4 genes 4936 Interactions with Vitamin D, Genetics , Inflammation, Vitamin D Receptor, CYP27B1 07 Feb, 2020
Vitamin D may be a magic bullet for the cells (not based on Vitamin D blood tests) – Jan 2020 3491 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 11 Jan, 2020
Eye vitamin D may not be associated with blood VitD, but is associated with CYP27B1 and CYP24A1 – Nov 2019 2967 Vision, Genetics , CYP27B1 18 Nov, 2019
Acute Coronary Syndrome is associated with poor Vitamin D genes (CYP27B1, CYP24A1) – Nov 2019 2534 Cardiovascular, Genetics , CYP27B1 15 Nov, 2019
Vitamin D deficiency is associated with 35 genes, only 7 of are commercially tested – Nov 2019 3971 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Nov, 2019
Body may change gene activation if more Vitamin D is needed (Schizophrenia in this case) – Oct 2018 Genetics , Cognitive, Vitamin D Receptor, CYP27B1 09 May, 2019
Cancer treatment by Vitamin D sometimes is restricted by genes – Oct 2018 6028 Cancer - Breast, Cancer, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 01 Nov, 2018
Vitamin D gene expression varies with Epileptic age – March 2018 3456 Genetics , Vitamin D Receptor, Epilepsy, CYP27B1 20 Mar, 2018
Brain may deal with all forms of Vitamin D (rat brain) – Sept 2017 7169 Genetics , Vitamin D Receptor, CYP27B1 06 Nov, 2017
Review of 11 Vitamin D genes – Nov 2017 3545 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Nov, 2017
UVB effects on genes of those with and without Psoriasis – April 2014 6431 UV and Vitamin D, Psoriasis, Genetics , CYP27B1 05 Aug, 2017
UVB increases vitamin D even if poor kidney by changing CYP27B1 genes in skin – Dec 2013 4025 UV and Vitamin D, Kidney, Genetics , Skin, CYP27B1 05 Aug, 2017
Colon cancer 30 percent more likely if problems with Vitamin D genes CYP24A1 or CYP27B1 – Nov 2015 3857 Cancer - Colon, Genetics , CYP27B1 16 Nov, 2015
Prostate Cancer – Vitamin D – CYP27B1 – CYP24 – June 2011 6337 Cancer - Prostate, Genetics , CYP27B1 16 Nov, 2015
Genes such as CYP27B1, CYP24A1 and Vitamin D – JAMA Nov 2012 6893 Genetics , CYP27B1 16 Nov, 2015
Vitamin D levels are strongly associated with genes: overview of twin studies – Nov 2012 20323 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Jan, 2015

36 pages in both categories: CYP27B1 + Vitamin D Receptor

Page Hits Categories Major change
People who do not catch COVID have a gene mutation (HLA-DQA2) which INCREASES cellular Vitamin D – June 2024 11 Vitamin D Receptor, CYP27B1 30 Aug, 2024
Obesity is associated with 1 to 5 poor vitamin D genes (childhood obesity in the case) – July 2024 9 Obesity, Genetics , Infant-Child, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 16 May, 2024
Gestational Diabetes and Vitamin D - many studies Pregnancy, Genetics , Vitamin D Receptor, CYP27B1 10 Apr, 2024
Gestational Diabetes and Vitamin D - many studies Pregnancy, Genetics , Vitamin D Receptor, CYP27B1 10 Apr, 2024
COVID maximum downregulation of Vitamin D receptor and CYP27B1 resulted in death - Feb 2024 12 Vitamin D Receptor, Virus, CYP27B1 14 Mar, 2024
Vitamin D and it’s related genes regulate the immune system – Aug 2023 903 Autoimmune, Immunity, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 13 Aug, 2023
12 Vitamin D genes (Most are not noticed by blood test) – Sept 2021 400 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 16 Jul, 2023
Cervical Cancer is prevented by Vitamin D, and treated if caught early (genes are important) – May 2023 439 Genetics , Cancer - Other, Vitamin D Receptor, CYP27B1 27 May, 2023
Response to Vitamin D - many studies 1480 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 07 Apr, 2023
Vitamin D genes vary with UVB in Europe, Africa, Asia – March 2020 373 UV and Vitamin D, Genetics , Middle East, Vitamin D in Europe, Vitamin D Receptor, Vit D Binding Protein, Orient, CYP27B1, Africa 06 Apr, 2023
Vitamin D genes may be more important than (25(OH)D) to orthopedics – Review Dec 2022 1943 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 08 Dec, 2022
COVID virus alters the activation of 100 vitamin D related genes in the lung – April 2021 2209 Genetics , Vitamin D Receptor, Vit D Binding Protein, Virus, CYP27B1 16 Aug, 2022
An ocular disease can be associated with low vitamin D and 1 of 5 poor vitamin D genes – June 2022 1365 Vision, Genetics , Vitamin D Receptor, CYP27B1 24 Jul, 2022
Vitamin D genes – Review June 2022 2539 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 30 Jun, 2022
Vitamin D metabolism and genes as of Nov 2019 1494 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 13 Jun, 2022
Poor vision associated with poor Vitamin D or poor Vit. D genes – June 2022 1592 Vision, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 05 Jun, 2022
Vitamin D levels in cells, not blood, is important (IVF follicular fluid in this case) – Aug 2021 2296 Fertility and sperm, Genetics , Top news, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 27 Apr, 2022
Better handgrip strength if some good vitamin D genes (or if supplement) – April 2022 1431 Sports and Vitamin D, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 09 Apr, 2022
Does survival of the less fit mean less health (poor genes may be inherited) 3328 Genetics , Top news, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 15 Feb, 2022
Breast Cancer, Vitamin D, and genes – Welsh Nov 2021 2114 Cancer - Breast, Vitamin D Receptor, CYP27B1 09 Feb, 2022
Breasts process Vitamin D and change gene activation, might prevent breast cancer if given more Vit. D – July 2021 3034 Cancer - Breast, Vitamin D Receptor, CYP27B1 10 Jul, 2021
Mucosal membranes (mouth, lungs, nose, intestines, etc) can activate Vitamin D – July 2020 3596 Breathing, Forms of Vitamin D, Genetics , Inflammation, Vitamin D Receptor, CYP27B1 14 Sep, 2020
Vitamin D genes are important, update – Sept 2020 2152 Genetics , Vitamin D Receptor, CYP27B1 12 Sep, 2020
Vitamin D in the blood encounters many restrictions in getting to the cells – Sept 2020 3944 Vitamin D Receptor, Vit D Binding Protein, CYP27B1 11 Sep, 2020
Parathyroid increase with age associated with worsening Vitamin D genes – April 2020 3891 Seniors, Genetics , Thyroid and parathyroid, Vitamin D Receptor, CYP27B1 01 May, 2020
Infant and child immunity depends on Vitamin D and two Vitamin D genes – Review April 2020 3973 Immunity, Infant-Child, Vitamin D Receptor, CYP27B1 27 Apr, 2020
Glucocorticoid treatment reduces Vitamin D getting to cells via 3 or 4 genes 4936 Interactions with Vitamin D, Genetics , Inflammation, Vitamin D Receptor, CYP27B1 07 Feb, 2020
Vitamin D may be a magic bullet for the cells (not based on Vitamin D blood tests) – Jan 2020 3491 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 11 Jan, 2020
Vitamin D deficiency is associated with 35 genes, only 7 of are commercially tested – Nov 2019 3971 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Nov, 2019
Body may change gene activation if more Vitamin D is needed (Schizophrenia in this case) – Oct 2018 Genetics , Cognitive, Vitamin D Receptor, CYP27B1 09 May, 2019
Cancer treatment by Vitamin D sometimes is restricted by genes – Oct 2018 6028 Cancer - Breast, Cancer, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 01 Nov, 2018
Vitamin D gene expression varies with Epileptic age – March 2018 3456 Genetics , Vitamin D Receptor, Epilepsy, CYP27B1 20 Mar, 2018
Brain may deal with all forms of Vitamin D (rat brain) – Sept 2017 7169 Genetics , Vitamin D Receptor, CYP27B1 06 Nov, 2017
Review of 11 Vitamin D genes – Nov 2017 3545 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Nov, 2017
Lungs with cystic fibrosis fail to activate vitamin D (poor CYP27B) – Feb 2016 5178 Cystic Fibrosis, Vitamin D Receptor, CYP27B1 10 Apr, 2017
Vitamin D levels are strongly associated with genes: overview of twin studies – Nov 2012 20323 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Jan, 2015

22 pages in both categories: CYP27B1 + Vit D Binding Protein

Page Hits Categories Major change
Obesity is associated with 1 to 5 poor vitamin D genes (childhood obesity in the case) – July 2024 9 Obesity, Genetics , Infant-Child, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 16 May, 2024
Vitamin D and it’s related genes regulate the immune system – Aug 2023 903 Autoimmune, Immunity, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 13 Aug, 2023
12 Vitamin D genes (Most are not noticed by blood test) – Sept 2021 400 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 16 Jul, 2023
Gene variants can reduce Vitamin D response by 1.7X (14,000 IU daily, Multiple Sclerosis) – Dec 2021 461 Multiple Sclerosis, Vit D Binding Protein, CYP27B1 15 Jul, 2023
Response to Vitamin D - many studies 1480 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 07 Apr, 2023
Vitamin D genes vary with UVB in Europe, Africa, Asia – March 2020 373 UV and Vitamin D, Genetics , Middle East, Vitamin D in Europe, Vitamin D Receptor, Vit D Binding Protein, Orient, CYP27B1, Africa 06 Apr, 2023
Vitamin D genes may be more important than (25(OH)D) to orthopedics – Review Dec 2022 1943 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 08 Dec, 2022
Brain cells can probably activate Vitamin D without liver or kidney (at least in rats) – Sept 2017 3387 Genetics , Vit D Binding Protein, CYP27B1 25 Oct, 2022
COVID virus alters the activation of 100 vitamin D related genes in the lung – April 2021 2209 Genetics , Vitamin D Receptor, Vit D Binding Protein, Virus, CYP27B1 16 Aug, 2022
Vitamin D genes – Review June 2022 2539 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 30 Jun, 2022
Vitamin D metabolism and genes as of Nov 2019 1494 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 13 Jun, 2022
Poor vision associated with poor Vitamin D or poor Vit. D genes – June 2022 1592 Vision, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 05 Jun, 2022
Vitamin D levels in cells, not blood, is important (IVF follicular fluid in this case) – Aug 2021 2296 Fertility and sperm, Genetics , Top news, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 27 Apr, 2022
Better handgrip strength if some good vitamin D genes (or if supplement) – April 2022 1431 Sports and Vitamin D, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 09 Apr, 2022
Does survival of the less fit mean less health (poor genes may be inherited) 3328 Genetics , Top news, Vitamin D Receptor, Vit D Binding Protein, CYP27B1 15 Feb, 2022
Vitamin D in the blood encounters many restrictions in getting to the cells – Sept 2020 3944 Vitamin D Receptor, Vit D Binding Protein, CYP27B1 11 Sep, 2020
Vitamin D may be a magic bullet for the cells (not based on Vitamin D blood tests) – Jan 2020 3491 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 11 Jan, 2020
Vitamin D deficiency is associated with 35 genes, only 7 of are commercially tested – Nov 2019 3971 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Nov, 2019
Increased risk of various cancers if poor vitamin D genes (Binding Protein and CYP27B1) - Sept 2019 3033 Cancer - Breast, Cancer - Other, Vit D Binding Protein, CYP27B1 25 Sep, 2019
Cancer treatment by Vitamin D sometimes is restricted by genes – Oct 2018 6028 Cancer - Breast, Cancer, Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 01 Nov, 2018
Review of 11 Vitamin D genes – Nov 2017 3545 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Nov, 2017
Vitamin D levels are strongly associated with genes: overview of twin studies – Nov 2012 20323 Genetics , Vitamin D Receptor, Vit D Binding Protein, CYP27B1 04 Jan, 2015

3 pages in both categories: CYP27B1 + Vision

4 pages in both categories: CYP27B1 + Cancer - Breast

3 pages in both categories: CYP27B1 + Kidney

3 pages in both categories: CYP27B1 + Top news

3 pages in both categories: CYP27B1 + Cognitive

5 pages in both categories: CYP27B1 + Pregnancy

3 pages in both categories: CYP27B1 + UV and Vitamin D

Created by admin. Last Modification: Sunday March 31, 2024 23:53:16 GMT-0000 by admin. (Version 42)
CYP27B1        
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