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Vitamin D Receptor activators (Resveratrol, Curcumin ,Quercetin) all improve bone – Review Aug 2022

Effects of Resveratrol, Curcumin and Quercetin Supplementation on Bone Metabolism—A Systematic Review

Nutrients 2022, 14(17), 3519; https://doi.org/10.3390/nu14173519
by Alessio Danilo Inchingolo et all

Phenolic compounds are natural phytochemicals that have recently reported numerous health benefits. Resveratrol, curcumin, and quercetin have recently received the most attention among these molecules due to their documented antioxidant effects. The review aims to investigate the effects of these molecules on bone metabolism and their role in several diseases such as osteopenia and osteoporosis, bone tumours, and periodontitis. The PubMed/Medline, Web of Science, Google Scholar, Scopus, Cochrane Library, and Embase electronic databases were searched for papers in line with the study topic. According to an English language restriction, the screening period was from January 2012 to 3 July 2022, with the following Boolean keywords: (“resveratrol” AND “bone”); (“curcumin” AND “bone”); (“quercetin” AND “bone”). A total of 36 papers were identified as relevant to the purpose of our investigation. The studies reported the positive effects of the investigated phenolic compounds on bone metabolism and their potential application as adjuvant treatments for osteoporosis, bone tumours, and periodontitis. Furthermore, their use on the titanium surfaces of orthopaedic prostheses could represent a possible application to improve the osteogenic processes and osseointegration. According to the study findings, resveratrol, curcumin, and quercetin are reported to have a wide variety of beneficial effects as supplement therapies. The investigated phenolic compounds seem to positively mediate bone metabolism and osteoclast-related pathologies.
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VitaminDWiki - 6 studies in both categories VDR and Bone

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VitaminDWiki - Vitamin D Receptor activation can be increased in 14 ways

Resveratrol,  Omega-3,  Magnesium,  Zinc,   Quercetin,   non-daily Vit D,  Curcumin, intense exercise, Butyrate   Ginger,   Essential oils, etc  Note: The founder of VitaminDWiki uses 10 of the 14 known VDR activators

VitaminDWiki - The Vitamin D Receptor is associated with many health problems

Health problems include: Autoimmune (19 studies), Breast Cancer (24 studies), Colon Cancer (14 studies), Cardiovascular (23 studies), Cognition (16 studies), Diabetes (25 studies), Hypertension (9 studies), Infant (22 studies), Lupus (6 studies), Metabolic Syndrome (4 studies), Mortality (4 studies), Multiple Sclerosis (16 studies), Obesity (17 studies), Pregnancy (25 studies), Rheumatoid Arthritis (10 studies), TB (8 studies), VIRUS (39 studies),   Click here for details
Some health problems, such as Breast Cancer, Diabetes, and COVID protect themselves by reducing VDR activation

VitaminDWiki pages with Vitamin D Receptor or VDR in title (400 as of Oct 2022)

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Items found: 452
Title Modified
Hypertension, Vitamin D, and Vitamin D Receptor – Aug 2019 08 Aug, 2019
Autoimmunity problems often associated with poor Vitamin D Receptors – March 2019 31 Jul, 2019
Septic children have low Vitamin D (54 studies, ignored Vitamin D Receptor) – meta-analysis April 2019 31 Jul, 2019
Breast Cancer death 1.8 X more likely if poor Vitamin D Receptor – April 2019 29 Jul, 2019
Breast Cancer death 1.8 X more likely if poor vitamin D Receptor – July 2019 29 Jul, 2019
Vitamin D Receptor, the gut, the immune system, and the Middle East – May 2019 14 Jul, 2019
Vitamin D Receptor - activation and deactivation- self-hacked June 2019 14 Jul, 2019
MRSA Carriers not helped by 4,000 IU of Vitamin D (probably poor Vitamin D Receptor) – RCT Sept 2018 14 Jul, 2019
Graves' disease 1.4 X more likely if poor Vitamin D Receptor – March 2019 12 Jul, 2019
TB patients had low Vitamin D and poor Vitamin D receptor – June 2019 01 Jul, 2019
Gestational Diabetes 2.4X more likely if poor Vitamin D Receptor (region in China) – June 2019 24 Jun, 2019
Lumbar disc degeneration 30 percent more likely if poor Vitamin D Receptor – May 2019 20 Jun, 2019
Tuberculosis increased risk if poor Vitamin D receptor varies by race – meta-analysis Feb 2019 20 Jun, 2019
Vitamin D Receptor synonyms 14 Jun, 2019
Blood cell cancer is associated with a 3X worse Vitamin D Receptor – June 2019 14 Jun, 2019
Vitamin D Receptor described at US National Library of Medicine 13 Jun, 2019
Inflammatory bowel disease, gut bionome and Vitamin D Receptor – 2018 13 Jun, 2019
Lung Cancer more likely if poor Vitamin D Receptor – meta-analysis June 2019 13 Jun, 2019
TB and Leprosy are easily confused and associated with Vitamin D Receptor 10 Jun, 2019
Best supplements for hay fever (Quercetin, which activates the Vitamin D receptor) - June 2019 05 Jun, 2019
After breast cancer treatment 4,000 IU of Vitamin D was not enough to help if have poor Vitamin D receptor – June 2019 04 Jun, 2019
Tuberculosis association with Vitamin D Receptor varies a lot with race – meta-analysis May 2019 30 May, 2019
Multiple Sclerosis and Vitamin D Receptor super enhancers – March 2019 23 May, 2019
Lupus in children 2.6 X more likely if they had poor Vitamin D Receptor – Jan 2017 20 May, 2019
Gestational Diabetes 3 X more likely if poor Vitamin D receptor (Turkey) – May 2019 18 May, 2019
Curcumin may increase Vitamin D in tissues (activates Vitamin D Receptor) – Dec 2010 04 May, 2019
Hodgkin’s lymphoma and Vitamin D Receptor - June 2012 29 Apr, 2019
Resveratrol prevented bone loss associated with T2DM (probably via VDR) – RCT Sept 2018 29 Apr, 2019
Arthritis runs in Pakistani families (Vitamin D Receptor) – March 2019 24 Apr, 2019
Hypertension, Vitamin D Receptor, and FokI gene – Editorial Aug 2014 23 Apr, 2019
Preeclampsia 2X more likely if poor Vitamin D Receptor – April 2019 23 Apr, 2019
Certain types of Tuberculosis are 2X more likely with a poor Vitamin D Receptor – April 2019 20 Apr, 2019
Skin fold thickness but not BMI associated with poor Vitamin D Receptor in Han Chinese – April 2018 13 Apr, 2019
Good Vitamin D receptor reduced bladder cancer and cisplatin deaths – April 2019 11 Apr, 2019
Ulcerative Colitis – half have poor level of Vitamin D Receptor vs only one in ten normally – June 2017 01 Apr, 2019
A poor Vitamin D Receptor is associated with many cancers (oral cancer in this case) – Jan 2019 26 Mar, 2019
Alzheimer’s (1.2X) and Parkenson’s (1.3X) more likely if poor Vitamin D Receptor – meta-analysis March 2019 23 Mar, 2019
Heart Failure 15X more likely if poor VDR, even if good level of vitamin D (China) – March 2019 23 Mar, 2019
Diabetic nephropathy deactivates the Vitamin D Receptor, reducing tissue Vit D – Feb 2019 01 Mar, 2019
Vitamin D and Ageing (29 page chapter, VDR decreases with age) – Feb 2019 23 Feb, 2019
Many autoimmune diseases associated with latitude and vitamin D receptor – March 2016 22 Feb, 2019
Upper respiratory infection associated with poor Vitamin D Receptor – Oct 2018 16 Feb, 2019
Respiratory Distress Syndrome in preemies 5 X more likely if poor vitamin D receptor – Feb 2019 15 Feb, 2019
Women with Breast Cancer were 16.9 times more likely to have a poor Vitamin D Receptor – Jan 2019 11 Feb, 2019
Progesterone activates vitamin D receptor - many studies 05 Feb, 2019
Treating herpes reduced incidence of senile dementia by 10 X (HSV1 reduces VDR by 8X) – 2018 17 Jan, 2019
Resveratrol gets vitamin D to cells even if poor vitamin D receptor 17 Jan, 2019
World's Top Authors in Vitamin D, VDR, Vitamin K, Omega-3, etc - Jan 2019 12 Jan, 2019
Vitamin D receptors get worse with age with osteoporosis – Dec 2018 30 Dec, 2018
Sleep Apnea 1.8 X more likely if poor Vitamin D Receptor – Dec 2018 21 Dec, 2018
Gut and airway bionome are affected by Vitamin D and Vitamin D Receptor – Nov 2018 16 Dec, 2018
Osteoporosis 15 percent more likely if poor Vitamin D receptor – meta-analysis Dec 2018 11 Dec, 2018
Risks of Colorectal Cancer, IBD, etc slightly increased if poor Vitamin D Receptor – Aug 2018 09 Dec, 2018
Upper respiratory infection 15 percent more likely if poor Vitamin D receptor– Oct 2018 09 Dec, 2018
Vitamin D receptor mutations might cause hereditary vitamin D-resistant rickets – March 2015 08 Dec, 2018
Impaired Vitamin D Sensitivity (Vitamin D Receptor) – Nov 2018 02 Dec, 2018
Psoriasis risk in Caucasians is 1.3 X higher if poor Vitamin D Receptor – meta-analysis Nov 2018 27 Nov, 2018
Severe hand, foot, and mouth virus is 2.9 X more likely if poor Vitamin D receptor – Oct 2018 23 Nov, 2018
Vitamin D Receptor in vitiligo skin activated by UVB – May 2018 11 Nov, 2018
Ovarian Cancer risk reduced if higher vitamin D, more UVB, or better vitamin D receptor – Nov 2018 10 Nov, 2018
Vitamin D Receptor – environment, genetics and epigenetics – May 2015 13 Oct, 2018
Bone density improved with resveratrol (which improves Vitamin D Receptor) – RCT Sept 2018 22 Sep, 2018
Many health risks associated with low Vit D or poor Vitamin D Receptor – more RCT needed – March 2018 18 Sep, 2018
Alzheimer’s associated with Vitamin D and Vitamin D receptor – video and pdf – Aug 2018 02 Sep, 2018
Preterm births 12 X more likely if poor Vitamin D Receptor (white infants in Italy) – meta-analysis Aug 2018 27 Aug, 2018
Juvenile idiopathic arthritis 2.2 X more likely if poor Vitamin D Receptor – Aug 2018 25 Aug, 2018
Skin and oral wounds treated via Vitamin D Receptor and Calcium (book chapter) – Feb 2018 22 Aug, 2018
Type 1 diabetes 1.6 times more likely if a Vitamin D Receptor problem – Feb 2017 21 Aug, 2018
Pneumonia in Egyptian Children 3.6 X more likely if poor Vitamin D Receptor – Aug 2018 15 Aug, 2018
Pancreatic Cancer – live a year longer if have high vitamin D and good Vitamin D Receptor – Aug 2018 15 Aug, 2018
Some enveloped virus are 1.2 X more likely if have a poor Vitamin D Receptor -Aug 2018 10 Aug, 2018
Endometriosis, Endometrial Cancer, and poor Vitamin D or Receptor – Aug 2018 08 Aug, 2018
Vitiligo (spotty skin coloring) is 4 X more likely if poor Vitamin D Receptor – meta-analysis July 2018 22 Jul, 2018
PCOS (polycystic ovary syndrome) 4 times more likely if poor Vitamin D Receptor – Dec 2015 11 Jul, 2018
Vitamin D Receptor and autoimmune diseases – Jan 2017 11 Jul, 2018
Risk of colon cancer increases in mice with no Vitamin D receptor in colon - July 2018 07 Jul, 2018
Sudden kidney infection in children was 9X more likely if poor Vitamin D receptor – July 2018 06 Jul, 2018
Autism associated with low Zinc during pregnancy (Zinc is needed by Vitamin D Receptor) – July 2018 02 Jul, 2018
Vitamin D receptor (TT), which restricts Vit D to cells, is associated with balance problems in seniors – June 2018 01 Jul, 2018
ADHD associated with both low vitamin D and poor Vitamin D receptor – May 2018 24 Jun, 2018
Cerebral small vessel disease 2.5 X more likely if poor Vitamin D Receptor – Sept 2018 23 Jun, 2018
Vitamin D receptor is essential for both normal and cancerous cells in the lab – June 2018 16 Jun, 2018
Vitamin D Receptor Signaling and Cancer – Dec 2017 16 Jun, 2018
Familial Mediterranean Fever is 3X more likely if poor Vitamin D Receptors (males) – Sept 2017 13 Jun, 2018
UV at time of conception associated with Vitamin D Receptor activation 65 years later – Sept 2017 15 May, 2018
Adolescent idiopathic scoliosis 2 X more likely in Asians with poor Vitamin D Receptor 08 May, 2018
Neonatal Sepsis 4.8 X more likely if poor Vitamin D receptor – June 2018 22 Apr, 2018
Thyroid and vitamin D are the only body components which have a receptor on every cell in the body 19 Apr, 2018
Pulmonary Tuberculosis 2X more likely if poor Vitamin D Receptor (Mexico) – April 2018 14 Apr, 2018
Vitamin D receptor is activated somewhat by ginger, thyme, coriander, and lemongrass – March 2018 08 Apr, 2018
Lumbar Degenerative Disc Disease 3X more likely if poor Vitamin D Receptor – March 2018 02 Apr, 2018
Active Vitamin D reduces Ovarian Cancer stem cells growth by 4X (via Vitamin D receptor in lab rat) – March 2018 28 Mar, 2018
Degeneration of lumbar disc 2.5 X more likely if poor Vitamin D receptor (not detected by test) Feb 2018 26 Mar, 2018
Metabolic Syndrome risk increases about 70 percent if poor Vitamin D Receptor 20 Mar, 2018
Two chemicals increase the Vitamin D receptor and decrease the growth of breast cancer cells in the lab - March 2018 17 Mar, 2018
Sepsis in infants 4.8 X more likely if poor vitamin D receptor – March 2018 14 Mar, 2018
Respiratory Tract Infections in children 7.4 X more likely if poor Vitamin D Receptor – 2008 11 Feb, 2018
Disc Degeneration in women is 1.7X more likely if poor Vitamin D Receptor – meta-analysis Jan 2017 04 Feb, 2018
Do you have a Vitamin D Receptor Mutation (and might need more vitamin D) – Jan 2018 24 Jan, 2018
Juvenile Rheumatoid Arthritis 8 X more likely if poor Vitamin D receptor – Dec 2017 03 Jan, 2018
Created by admin. Last Modification: Monday October 3, 2022 16:22:58 GMT-0000 by admin. (Version 7)
Vitamin D Receptor activators (Resveratrol, Curcumin ,Quercetin) all improve bone – Review Aug 2022        
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