Table of contents
- Low Magnesium results in poor health - GRH Nov 2019
- Direct and indirect associations between dietary magnesium intake and breast cancer risk - 2019
- See also VitaminDWiki
- Magnesium and some other Health categories in VitaminDWiki
- Magnesium in Breast Cancer: What Is Its Influence on the Progression of This Disease? - Aug 2018
Low Magnesium results in poor health - GRH Nov 2019
How Magnesium Could Impact Cancer Risk GrassrootsHealth Nutrient Institute
Direct and indirect associations between dietary magnesium intake and breast cancer risk - 2019
Sci Rep. 2019 Apr 8;9(1):5764. doi: 10.1038/s41598-019-42282-y.
Huang WQ1,2, Long WQ3, Mo XF4, Zhang NQ1, Luo H1, Lin FY5, Huang J1, Zhang CX6,7.
Associations shown include Mg: Ca, but not Mg:Vitamin D
This study aimed to explore the effect of dietary magnesium intake on breast cancer risk both directly and indirectly via its effect on inflammatory markers C-reactive protein (CRP) and interleukin-6 (IL-6). This case-control study recruited 1050 case patients and 1229 control subjects. Inflammatory marker levels of 322 cases and 322 controls, randomly selected, were measured using ELISA, and data on dietary magnesium intake were collected using a food frequency questionnaire. Multivariable logistic regression was used to estimate the odds ratio (OR) and 95% confidence interval (CI), and path analysis was used to investigate the mediating effect. A higher magnesium intake was associated with a lower breast cancer risk (adjusted OR = 0.80, 95% CI = 0.65, 0.99). A positive association was found between the CRP level and breast cancer risk (adjusted OR = 1.43, 95% CI = 1.02-2.01). However, IL-6 was not found to be associated with breast cancer risk. Path analysis revealed that dietary magnesium affected breast cancer risk both directly and indirectly by influencing the CRP level. The results indicate that a direct negative association and an indirect association through influencing the CRP level were observed between dietary magnesium intake and breast cancer risk.
See also VitaminDWiki
Magnesium and Vitamin D contains the following summary
- Overview Magnesium and vitamin D
- Longevity experts take Vitamin D, Omega-3, and Magnesium - Patrick video Sept 2023
- The ONE Supplement All Longevity Experts Are Taking (Magnesium) - video and transcript Dec 2023
- Magnesium deficiency – causes and symptoms – May 2016
- Magnesium Depletion Score predicts increased risk of various health problems
- Vitamins and Metals needed by the Immune System – Jan 2020
- Magnesium: intake decreased, difficult to measure in body – Sept 2018
- Magnesium deficiency estimated by just 6 Yes No questions - Dec 2019
- Magnesium fights diabetes (yet again)– meta-analysis Nov 2021
- Magnesium in Healthcare (Rickets, Stones, Pregnancy, Depression, etc.) with level of evidence – Sept 2017
- Magnesium is great for health, topical much faster than oral, MgCl2 is the best – 2019
- Magnesium is important for health but levels are low – July 2018
- How to get lots of Magnesium – especially needed for Coimbra MS and Autoimmune Protocol
- Magnesium etc. reduced in crops (must supplement) – 2009
Mg and Vitamin D
- Intracellular Magnesium and Vitamin D - a few studies
- Vitamin D and Magnesium need each other - many studies
- Why Vitamin D is Useless without This Critical Nutrient (Magnesium) - Jan 2019
- 500 mg of Magnesium for 8 weeks increased Vitamin D by 4 ng – July 2020
- Magnesium and Vitamin D - pre-colon cancer – RCT Dec 2018
- Magnesium is vital to Vitamin D in 4 places (maybe 8) – March 2018
- Magnesium and Vitamin D – recent deficiencies, needed, synergistic - good overview 2017
- Vitamin D Cofactors in a nutshell
- Magnesium and Vitamin D - similar, different and synergistic
Magnesium topics gathered on a page
- Vitamin D, Omega-3, and Magnesium are synergistic - many studies
- Magnesium and Cancer - many studies
- Diabetes, Metabolic Syndrome and Magnesium - many studies
- Low Magnesium associated with severe COVID – many studies
- Calcium to Magnesium Ratio - many studies
- Magnesium Role in Health and Longevity - many studies
- Magnesium reduces pain - many studies
- Vitamin D and Magnesium need each other - many studies
- Pregnancy helped by Magnesium - many studies
Overview Magnesium and vitamin D Has a venn diagram of relationship of Mg and Vit D
| Magnesium | not Magnesium | |
| Vitamin D | Magnesium or Vitamin D Aging, Amyotrophic Lateral Sclerosis, Alzheimer's Disease; Asthma, Attention Deficit Disorder, Autism, Cancer, Cerebrovascular, Chronic Fatigue, Diabetes, Hearing Loss, Heart Disease, Heart Attack, Atherosclerosis, Cardiovascular Disease, HIV, AIDS; Hypertension; Kidney Stones, Migraine Headache, Multiple Sclerosis, Obesity, Osteoporosis, Peripheral vascular disease; Pregnancy-related problems, Rheumatoid Arthritis, Sports-related problems, | Vitamin D only Acne, Allergy, Autoimmune, Bone, Breathing, Celiac, Cognition, Colds and Flu, Cystic Fibrosis, Dental, Fertility, hyperparathyroid, Immunity, Kidney, Liver, Lupus, Osteoarthritis, Pain - chronic, Parkinson, Psoriasis, Rickets, Strokes, Sarcoidosis, Thyroid, Parathyroid, Tuberculosis, Vision, Hair, Skin, Sports |
| Not Vitamin D | Magnesium only Aggressive Behavior, Alcoholism, Arrhythmia, Cerebral Palsy, Chemical Sensitivity, Cluster Headaches; Cocaine-related Stroke; Constipation, Cramps, Fluoride Toxicity, Head Injuries, Central Nervous System Injuries, Magnesium Deficiency; Menopause, Mitral Valve Prolapse, Nystagmus, Psychiatric Disorders; Repetitive Strain Injury, Sickle Cell Disease, SIDS, Stress, Stuttering, Tetanus; Tinnitus, Sound Sensitivity; TMJ; Toxic Shock; Violence | Neither ALL OTHER DISEASES |
Magnesium and some other Health categories in VitaminDWiki
Magnesium and Breast Cancer
- As Breast Cancer get worse, both Vitamin D and Magnesium crash – Oct 2024
- Low Magnesium results in poor health (Breast Cancer in this case) – Nov 2019
- Death after Breast Cancer 2 times less likely if take lots of Magnesium – Dec 2015
- Breast cancer associated with high Calcium AND low vitamin D - April 2015
- Hypothesis: increased breast cancer if not enough magnesium – Sept 2010
Magnesium and other Cancers
- Colon cancer 25 percent less likely if consume Calcium, Magnesium, Zinc, etc.– Nov 2018
- Colorectal Cancer risk increases 1.6 X if high Calcium, low Magnesium and a poor gene – Sept 2007
- Pancreatic Cancer risk increased 24 percent for every 100 mg less of Magnesium intake – Dec 2015
- Muscle pain (Low Magnesium) plus Low Vitamin D associated with 10X more Cancer, etc (San Francisco) – Aug 2017
Magnesium and Bone
- Which supplements are often taken for healing hairline bone fractures
- Magnesium helps bones a bit – meta-analysis Jan 2022
- Magnesium increases Vitamin D, which increases Mg. Both increase bone – Oct 2019
- Vitamin D and Calcium do not increase bone density (also need exercise, Mg, K2, protein etc.) – RCT Aug 2019
- Many seniors do not get enough protein, Vitamin D, Mg, etc. needed for bones – Feb 2019
- More Magnesium makes more bone when there is enough Vitamin D (petri dish) – Jan 2019
- Diagnosis and treatment of osteopenia – Holick 2010
- Adding just vitamin D again failed to add bone density (also need Magnesium, Vitamin K, etc) – RCT Aug 2018
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- Stronger bones after 3 generations of tap water (more Ca and Mg) vs bottled water – March 2015
- Bones grow better with high level of magnesium: rat study – Dec 2013
- 20 percent fewer male hip fractures if more Magnesium in the water – July 2013
- Magnesium may be more important to kids’ bone health than calcium – May 2013
- Healthy bones need: Calcium, Vitamin D, Magnesium, Silicon, Vitamin K, and Boron – 2012
- Vitamin D, K2, Magnesium, etc increase bone density when taking together– Jan 2012
- 400 IU of vitamin D Magnesium and Calcium helped Twin bones – Feb 2011
Magnesium and Cardiovascular
- More Magnesium needed to decrease diabetes, cardio, HT (body weight has increased) - March 2021
- Nitric oxide increased by UVA, Vitamin D, Magnesium, etc,
- Atrial Fibrillation decreased by Vitamin D or Magnesium - many studies
- Signs of low Magnesium (heart problems in this case) – Jan 2018
- Ablation does not reduce atrial fibrillation (CABANA study) but Magnesium does – June 2018
- Cardiometaboic problems decreased with increased Vitamin D, unless low Magnesium – Aug 2017
- Heart problems in obese increase if deficient in BOTH Vitamin D and Magnesium – Aug 2017
- Health problems prevented by eating nuts (perhaps due to Magnesium and or Omega-3) – meta-analysis Dec 2016
- Cardiovascular calcification prevented by Omega-3, Magnesium, Vitamin K, and Vitamin D – April 2015
- More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
- Atrial Fibrillation - remineralize your heart - Aug 2015
- Magnesium Suppresses Formation of Clogged Arteries - May 2014
- Off Topic: EDTA similar reduction in heart attack as Vitamin C, aspirin and Mg – RCT March 2013
- Death from Coronary Heart Disease related to low Magnesium intake – March 2013
- Magnesium prevents cardiovascular events – Meta-analysis March 2013
- Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
- Heart problems such as Afib related to little Magnesium, Omega-3, Vitamin D getting to tissues
Magnesium and Diabetes
- Retinopathy in males 6.9 X more likely if low vitamin D and low Magnesium - June 2024
- Magnesium Depletion Score predicts increased risk of various health problems
- High fluoride in water: 5X more likely to be Vitamin D deficient – Jan 2023
- Diabetes, Metabolic Syndrome and Magnesium - many studies
- More Magnesium needed to decrease diabetes, cardio, HT (body weight has increased) - March 2021
- Treating pre-diabetes with Magnesium Chloride should be cost effective – June 2022
- Reduced Magnesium is associated with reduced health (Diabetes in this case) - April 2022
- Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes - Jan 2021
- The Role of Magnesium in the Pathogenesis of Metabolic Disorders – April 2022
- Magnesium fights diabetes (yet again)– meta-analysis Nov 2021
- Excessive insulin decreases vitamin D in 4 ways – problems for diabetic COVID-19 – Dec 2020
- Low Magnesium associated with diabetes, etc. – meta-analysis 2016
- Low Level Laser Therapy greatly increased Vitamin D and Magnesium (for diabetics with nephropathy) – March 2019
- Young Diabetics had 3.8 X higher risk of Parkinson’s (perhaps low Mg or low Vitamin D)– June 2018
- Cardiometaboic problems decreased with increased Vitamin D, unless low Magnesium – Aug 2017
- Diabetes 29 % less likely if consume lots of Magnesium and cereal fiber (surveys of 200,000 people) – Oct 2017
- Magnesium is associated with prevention and treatment of Diabetes – Meta-analysis Aug 2016
- Type 2 diabetes associated with low Magnesium
- MAGNESIUM IN MAN - IMPLICATIONS FOR HEALTH AND DISEASE – review 2015
- More vitamin D makes for better health – dissertation based on Rotterdam studies – Oct 2015
- Prediabetes reduced in half by those getting Magnesium Chloride – RCT April 2015
- Type II Diabetes might be prevented and treated with Magnesium – Review Feb 2015
- Diabetes decreased with 300 mg of Mg (Mg Sulfate) – RCT July 2014
- Daily Magnesium improved all aspects of metabolic profile – RCT July 2014
- Diabetes and low Magnesium - Mercola 2014 - 2019
- Diabetics have problems with low Magnesium, especially if taking statins – Aug 2013
- Low Magnesium and type II diabetes – June 2012
- Hypothesis: Decreasing Magnesium and increasing CaMg ratio are increasing health problems – 2012 - 2013
- Reduced chance of diabetes 46 percent with Magnesium - Oct 2010
Magnesium and Obesity
- Magnesium in Obesity, Metabolic Syndrome, and Type 2 Diabetes - Jan 2021
- The Role of Magnesium in the Pathogenesis of Metabolic Disorders – April 2022
- More Magnesium needed by obese (Mg Sulfate, women in this case) – RCT Dec 2021
- PTH failed to decrease with Vitamin D if overweight and had low Magnesium – Aug 2019
- Magnesium may help with calorie restriction, ALS, and R-loops in DNA - LEF Oct 2017
- Heart problems in obese increase if deficient in BOTH Vitamin D and Magnesium – Aug 2017
- Obesity epidemic: a perfect storm of deficiency of vitamin D, Magnesium, Iodine, etc – May 2012
- Obesity pandemic since 1975 - is it due to Vitamin D, Magnesium, Iodine, adenovirus, or what
- Reasons for low response to vitamin D
- Weight loss and Vitamin D, Calcium, and Magnesium
- Overview Magnesium and vitamin D
Magnesium in Breast Cancer: What Is Its Influence on the Progression of This Disease? - Aug 2018
Biol Trace Elem Res. 2018 Aug;184(2):334-339. doi: 10.1007/s12011-017-1207-8
Mendes PMV1, Bezerra DLC1, Dos Santos LR1, de Oliveira Santos R1, de Sousa Melo SR1, Morais JBS1, Severo JS1, Vieira SC2, do Nascimento Marreiro D3.
- 1 Department of Nutrition, Federal University of Piauí, Ministro Petrônio Portella Campus, Ininga, Rua Hugo Napoleão, 665, Ed. Palazzo Reale, Apt°. 2001, Jóquei, Teresina, PI, CEP 64048-320, Brazil.
- 2 Department of Medicine, Federal University of Piauí, Ministro Petrônio Portella Campus, Ininga, Teresina, PI, Brazil.
- 3 Department of Nutrition, Federal University of Piauí, Ministro Petrônio Portella Campus, Ininga, Rua Hugo Napoleão, 665, Ed. Palazzo Reale, Apt°. 2001, Jóquei, Teresina, PI, CEP 64048-320, Brazil. dilina.marreiro at gmail.com.
Breast cancer is a disease of high mortality, characterized by the progressive accumulation of mutations that contribute to the uncontrolled development of breast tissue cells. Literature shows that disturbances in mineral homeostasis, such as magnesium, may interfere with tumor progression. The objective of this study is to provide updated information about magnesium's role in the pathogenesis of breast cancer. A review of literature was carried out from a search for articles in the PubMed and CAPES Periodicals databases published between 1995 and 2016 with the cross-references of the descriptors "magnesium," "breast neoplasms," and "oxidative stress" and the corresponding words in Portuguese. We included studies on the metabolism and bioavailability of magnesium and studies related to breast cancer and excluded articles in which only the abstract was available, dissertations, theses, articles involving adjuvant and/or neoadjuvant therapies, and supplementation of minerals in breast cancer patients. Magnesium is a mineral that participates in the metabolism of various nutrients and nucleic acids.
In the presence of breast cancer, neoplastic cells increase the expression of magnesium transport channels, which raises the intracellular concentration of the mineral, contributing to tumor growth through its function of increasing energy demand. The data obtained in this review illustrates the influence of magnesium on the progression of breast cancer. However, the existing data are scarce and inconsistent, which demonstrates a need for further studies on the subject with a goal to have better control of the disease.
?? Does this indicate increased Magnesium would INCREASE the growth of Breast Cancer??
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