Behavior disorders reduced with Magnesium, Omega-3, and Zinc

• ADHD and Vitamin D Deficiency category listing has 52 items along with related searches
  • ADHD associated with low vitamin D in all 8 trials – meta-analysis Oct 2018
  • Attention Deficit Hyperactivity Disorder impulsivity reduced by daily 1,000 IU of vitamin D – RCT Jan 2019
  • Attention-Deficit Hyperactivity Disorder treated by weekly 50,000 IU of vitamin D – RCT Nov 2018
  • Deficiencies of Vitamin D, Iron, Magnesium, and Zinc all associated with ADHD – Sept 2014
  • Vitamin D patented to treat ADHD – June 2018
• Vitamin D and Magnesium category listing has 369 items along with related searches
• Zinc and Vitamin D category listing has 90 items along with related searches
  • Olympic Committee consensus on Vitamin D, Omega-3, Zinc, etc– May 2018
• Depression category listing has 268 items along with related searches
  • Less depression in seniors taking enough Omega-3 – meta-analysis July 2018
  • Unipolar depression treated by Omega-3, Zinc, and probably Vitamin D – meta-analysis Oct 2017
  • Depression is associated with low Magnesium – meta-analysis April 2015

Note: Omega-3, Magnesium, and Zinc each increase the amount of vitamin Dactually getting to the tissues
Note: Behavior disorders also decrease if just Vitamin D is given

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All studies in BOTH categories ADHD and Omega-3

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All studies in BOTH categories Autism and Omega-3

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All studies in BOTH categories Depression and Omega-3

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All studies in BOTH categories Depression and Magnesium

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Dogs – Dec 2018

Effect of Supplementation With Omega-3 Fatty Acids, Magnesium, and Zinc on Canine Behavioral Disorders: Results of a Pilot Study
Top Companion Anim Med. 2018 Dec;33(4):150-155. doi: 10.1053/j.tcam.2018.08.006
Rahimi Niyyat M1, Azizzadeh M1, Khoshnegah J2.
1 Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran.
2 Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran. khoshnegah at um.ac.ir.

Recent discoveries have shown that the chances of a dog developing a behavioral disorder may depend upon a number of factors including nutrition. The current pilot study was designed to provide an assessment of the efficacy of a dietary supplement containing omega-3 fatty acids, magnesium, and zinc on some common behavioral disorders in a population of Iranian domestic dogs. In total, 48 dogs including 6 dogs without any behavior disorder (control group) and 42 dogs with at least 1 common behavioral disorder, namely excessive activity, inappropriate elimination, fearfulness, destructiveness, and aggression toward unfamiliar people and dogs (test group), were given daily oral dose of gelatin capsules of fish oil supplements containing 330 mg eicosapentaenoic acid and 480 mg docosahexaenoic acid.
Moreover, all (test group?) dogs received

• 12-15 mg/kg of magnesium citrate and
• 5 mg/kg of zinc sulfate.

Data were obtained using a questionnaire that dog owners were invited to fill out 2 times before (Days 0 and 42) and 2 times after the supplement treatment period (Days 84 and 126). The questionnaire asked owners whether their dog had exhibited any of the 6 common behavioral disorders on a 5-point Likert-like scale ranging from 0 (never or very rarely) to 4 (very often). The results showed no significant changes for any of the evaluated behavior disorders scale in the control group. In dogs with behavior disorders, results showed a significant reduction in the median score for the

• severity of fearfulness (P = .0083),
• destructiveness (P = .002), and
• inappropriate elimination (P < .001).

In addition, there were no significant differences in the median score for the severity of excessive activity (P = .162), aggression toward dogs (P = .281), and aggression toward unfamiliar people (P = .09) during the course of the study. Results of the study reported here support the hypothesis that a combination of omega-3 fatty acids, magnesium, and zinc may improve some of the behavioral disorders.

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ADHD Children - Sept 2010

Supplementation of polyunsaturated fatty acids, magnesium and zinc in children seeking medical advice for attention-deficit/hyperactivity problems - an observational cohort study
Lipids in Health and Disease 2010, DOI:10.1186/1476-511X-9-105
Michael Huss, Andreas Völp, Manuela Stauss-Grabo
 Download the PDF from VitaminDWiki

Background
Polyunsaturated fatty acids are essential nutrients for humans. They are structural and functional components of cell membranes and pre-stages of the hormonally and immunologically active eicosanoids. Recent discoveries have shown that the long-chained omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) also play an important role in the central nervous system. They are essential for normal brain functioning including attention and other neuropsychological skills.

Materials and methods
In our large observational study we monitored 810 children from 5 to 12 years of age referred for medical help and recommended for consuming polyunsaturated fatty acids (PUFA) in combination with zinc and magnesium by a physician over a period of at least 3 months. The food supplement ESPRICO® (further on referred to as the food supplement) is developed on the basis of current nutritional science and containing a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc. Study objective was to evaluate the nutritional effects of the PUFA-zinc-magnesium combination on symptoms of attention deficit, impulsivity, and hyperactivity as well as on emotional problems and sleep related parameters. Assessment was performed by internationally standardised evaluation scales, i.e. SNAP-IV and SDQ. Tolerance (adverse events) and acceptance (compliance) of the dietary therapy were documented.

Results
After 12 weeks of consumption of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc most subjects showed a considerable reduction in symptoms of attention deficit and hyperactivity/impulsivity assessed by SNAP-IV. Further, the assessment by SDQ revealed fewer emotional problems at the end of the study period compared to baseline and also sleeping disorders. Mainly problems to fall asleep, decreased during the 12 week nutritional therapy. Regarding safety, no serious adverse events occurred. A total of 16 adverse events with a possible causal relationship to the study medication were reported by 14 children (1.7%) and only 5.2% of the children discontinued the study due to acceptance problems. Continuation of consumption of the food supplement was recommended by the paediatricians for 61.1% of the children.

Conclusion
Our results suggest a beneficial effect of a combination of omega-3 and omega-6 fatty acids as well as magnesium and zinc consumption on attentional, behavioural, and emotional problems of children and adolescents. Thus, considering the behavioural benefit in combination with the low risk due to a good safety profile, the dietary supplementation with PUFA in combination with zinc and magnesium can be recommended