- SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE2 Dec 4 preprint FREE PDF
- SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2 March 31 - peer reviewed version of above preprint
- COVID-19 and the cardiovascular system Nature, March 5, FREE PDF
- Impact of Cardiovascular Diseases on COVID-19- A Systematic Review online March 6. FREE PDF
- Potential Effects of Coronaviruses on the Cardiovascular System A Review JAMA March 27, FREE PDF
- COVID-19 and Cardiovascular Disease Circulation Research, April 15. FREE PDF
- THE NOVEL CORONAVIRUS’ SPIKE PROTEIN PLAYS ADDITIONAL KEY ROLE IN ILLNESS Salk April 30
- "Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease"
- apparently the research was preprinted Dec 4, then peerprinted March 31 - above
- "In the new study, the researchers created a “pseudovirus” that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal model—proving that the spike protein alone was enough to cause disease. Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls.'
- "The team then replicated this process in the lab, exposing healthy endothelial cells (which line arteries) to the spike protein. They showed that the spike protein damaged the cells by binding ACE2. This binding disrupted ACE2’s molecular signaling to mitochondria (organelles that generate energy for cells), causing the mitochondria to become damaged and fragmented."
Now the breadth of the COVID-19 and perhaps long-haul symptoms have a context
- COVID-19 (coronavirus): Long-term effects MayoClinic April 13
- Common signs and symptoms that linger over time include:
- Fatigue, Shortness of breath or difficulty breathing, Cough, Joint pain, Chest pain. Memory, concentration or sleep problems
- Muscle pain or headache, Fast or pounding heartbeat. Loss of smell or taste. Depression or anxiety
- Fever, Dizziness when you stand. Worsened symptoms after physical or mental activities
Wonder how much of that is inflammation
COVID-19 treated by Vitamin D - studies, reports, videos
- As of March 31, 2024, the VitaminDWiki COVID page had: trial results, meta-analyses and reviews, Mortality studies see related: Governments, HealthProblems, Hospitals, Dark Skins, All 26 COVID risk factors are associated with low Vit D, Fight COVID-19 with 50K Vit D weekly Vaccines Take lots of Vitamin D at first signs of COVID 166 COVID Clinical Trials using Vitamin D (Aug 2023) Prevent a COVID death: 9 dollars of Vitamin D or 900,000 dollars of vaccine - Aug 2023
5 most-recently changed Virus entries
Items in both categories Virus and Cardiovascular are listed here:
- Virus and Cardiovascular problems - many studies
- Corpses with fiberous clots: 0% before COVID, 30% in 2022, 20% in 2023
- 2 reasons doctors not aware of post-vaccination myocarditis (2.5% of jabs) - Nov 2023
- Vaccine Clinical Trial - cardiovascular death 3.7X more likely if vaccinated - preprint Sept 2023
- Myocarditis, Pericarditis 2X more likely if had COVID vaccination in previous 30 days - meta-analysis June 2023
- COVID Vaccinations increased risk of cardiac deaths in youths by 19% - Aug 2023
- 800x Higher Incidence of Myocardial Injury After Booster Vaccination - July 2023
- Atrial Fibrillation - now 1 in 45 in the UK - May 2023
- Airline pilot heart annual EKGs - 1 in 5 would have failed test if FAA had not changed the criteria - Jan 2023
- Athletic deaths now 7 X higher than normal - Dec 2022
- High dose vitamin D fights Folate gene changes by COVID, autoimmune, CVD, ALZ – Oct 2022
- COVID and CVD deadly pandemics share a risk factor: low vitamin D - April 2022
- Omega-3 decreases heart disease and COVID: Harris and Patrick, video and transcript - Dec 2021
- Vitamin D probably has a Role in Cancer, CVD, and COVID - video and transcript Dec 1, 2021
- Growing consensus: COVID-19 symptoms are due to infected blood vessels - April 2021
- COVID-19 hospitalizations: 63% associated with diabetes, obesity, hypertension or heart failure – Feb 2021
- 26 health factors increase the risk of COVID-19 – all are proxies for low vitamin D
- COVID-19 deaths 4 to 7 X more likely if Diabetic, Hypertensive, or CVD - meta-analysis March 2020
- Low heart rate variability (bad) is associated with low Vitamin D and COVID – many studies
Items in both categories Virus and Inflammation are listed here:
- Inflammation causes low iron, which triggers long-COVID – March 2024
- Fasting may reduce inflammation and long-COVID - June 2023
- Vitamin D energizes the innate and adaptive immune systems to fight lung inflammation – Sept 2022
- COVID children with multisystem inflammatory syndrome have less than 10 ng of vitamin D – March 2022
- 8 of 10 pediatric COVID-19 infections were Vitamin D deficient (49 patients) – May 2021
- COVID-19 inflammation extinguished by 60,000 IU of vitamin D nanoemulsion daily for a week – RCT May 2021
- Hospitalized children with COVID-19 and inflammation had lower vitamin D – March 2021
- Vitamin D might reduce Multisystem Inflammatory Syndrome in children – March 2021
- COVID-19 deaths are proportional to previous interleukin-6 levels, Vitamin D lowers them – Nov 2020
- Malaria in mice brains, and associated inflammation, prevented by Vitamin D intervention – July 2014
Inflammation Intervention trials using Vitamin D:
- A small amount of Vitamin D for a short time does not help (2800 IU, 8 weeks) – RCT Oct 2021
- COVID-19 inflammation extinguished by 60,000 IU of vitamin D nanoemulsion daily for a week – RCT May 2021
- Diabetic inflammation reduced by Vitamin D (30,000 IU weekly) – RCT July 2020
- Type 2 Diabetes inflammation reduced by 50,000 IU of Vitamin D bi-weekly and resistance training – RCT – June 2019
- Urinary sepsis – a single Vitamin D injection reduced hospital days by 40 percent – RCT April 2018
- Can burn pain be relieved by 4 g of Omega-3 and 2,000 IU of vitamin D – RCT due 2021
- Eczema (Atopic Dermatitis) treated by 1600 IU of vitamin D – meta-analysis Dec 2016
- UTI associated with low Vitamin D as well as treated - many studies
- Inflammation reduced by a single dose of Vitamin D (200,000 IU) – RCT Jan 2016
- Anti-inflamatory cytokines increased when vitamin D levels were raised above 30 ng – RCT Feb 2015
- Diabetic inflammation reduced by Calcium and 50,000 IU of vitamin D in 8 weeks – RCT 2014
- Malaria in mice brains, and associated inflammation, prevented by Vitamin D intervention – July 2014
- Inflammation in African Americans not reduced with 3 months of 4000 IU of vitamin D – RCT Dec 2013
- Gingivitis inflammation (retracted) -Jan 2013
- 4000 IU vitamin D daily for just 5 days reduced inflammation after heart attack – RCT Jan 2013
- Atopic dermatitis dramatically reduced in Iran with 1600 IU of vitamin D – RCT March 2012
- Sepsis is both prevented and treated by Vitamin D - many studies
Some titles of pages in VitaminDWiki containing "long-haul"
Items found: 34
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