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Many chronic and acute diseases are fought by Vitamin D – June 2022

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Vitamin D: role in chronic and acute diseases -
VitaminDWiki - 11 Obesity Meta-analyses
VitaminDWiki - 40 Diabetes Meta-analyses
VitaminDWiki - 8 RA Meta-analyses
VitaminDWiki Meta-analyses with CANCER in title (72 as of June 2022)
VitaminDWiki Meta-analyses with COPD in title (6 as of June 2022)
VitaminDWiki - 44 COVID Meta-analyses

Vitamin D: role in chronic and acute diseases -

Reference Module in Food Science https://doi.org/10.1016/B978-0-12-821848-8.00101-3
Ana I.Álvarez-MercadoabMaría DoloresMesaabÁngelGilabc

Vitamin D is involved in bone health by promoting calcium absorption in the gut and maintaining serum calcium and phosphate concentrations, and by its action on bone growth and reorganization through osteoblasts and osteoclasts cells. Moreover, during the last three decades, novel actions of vitamin D have been discovered. Several systematic reviews and meta-analyses have shown links between serum vitamin D levels and non-communicable diseases. In line with these findings, a wide number of studies have suggested associations of vitamin D deficiency (VDD) with respiratory tract infections, osteoporosis, and other chronic and metabolic diseases such as obesity, metabolic syndrome, type 2 diabetes mellitus (T2DM), cancer, rheumatoid arthritis (RA), and inflammatory bowel disease (IBD). Vitamin D also exerts important actions in the clinical course of infectious and other acute diseases, particularly respiratory bacterial infections, tuberculosis, and virus infections, e.g., those generated by human immunodeficiency and SARS-CoV-2 (COVID-19) viruses. The present article aimed to update the role of vitamin D in chronic and acute diseases.

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VitaminDWiki - 11 Obesity Meta-analyses

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VitaminDWiki - 40 Diabetes Meta-analyses

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VitaminDWiki - 8 RA Meta-analyses

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VitaminDWiki Meta-analyses with CANCER in title (72 as of June 2022)

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Items found: 85

Title		Modified
Non-cancer colon growths 7 % less likely per 10 ng increase in Vitamin D – Oct 2011		08 Dec, 2024
Graphs of Vitamin D and Cancer – meta-analysis Dec 2011		08 Dec, 2024
Pancreatic cancer mortality 28% more likely if low vitamin D – meta-analysis Jan 2024		28 Nov, 2024
Analysis of 280 Breast Cancer meta-analyses: having low vitamin D was highly suggestive – umbrella July 2024		28 Jul, 2024
Bladder cancer in muscles 2.7 times more-likely if vitamin D less than 20 ng -meta-analysis May 2024		23 May, 2024
1.5X more likely to die of Prostate Cancer if low vitamin D when initially diagnosed – meta-analysis March 2024		13 Mar, 2024
Pancreatic Cancer survival 2.3 X more likely if good level of Vitamin D – meta-analysis Sept 2023		15 Sep, 2023
Thyroid Cancer 1.4 X higher risk if low vitamin D– meta-analysis Feb 2018		29 Aug, 2023
Death of women from cancer 24% less likely if 20 ng more vitamin D – meta-analysis Sept 2013		31 Jul, 2023
16 factors increase the risk of early-onset colorectal cancer, only vitamin D decreases the risk – meta-analysis May 2023		22 May, 2023
Breast Cancer not prevented by vitamin D when use small doses or for just a short time – Meta-analysis April 2023		11 May, 2023
Prostate Cancer death 40 percent less likely if 40 ng level of vitamin D – Meta-analysis Oct 2018		30 Apr, 2023
Breast Cancer risk - meta-analysis of 50 studies - Dec 2019		25 Mar, 2023
Ovarian Cancer 37 percent less likely if high vitamin D – meta-analysis March 2023		20 Mar, 2023
Colorectal Cancer 10 percent more likely if poor Vitamin D Receptor – meta-analysis Jan 2023		08 Jan, 2023
Colorectal cancer 14 percent less likely if 10 ng more Vitamin D – 22nd meta-analysis – Sept 2022		13 Sep, 2022
USPSTF says no evidence that Vitamins prevent CVD or Cancer (data disagrees) Aug 2022		05 Sep, 2022
Even after a Cancer diagnosis Vitamin D improves survival – meta-analysis Aug 2022		19 Aug, 2022
Colorectal cancer 40 percent less likely if 1000 IU more Vitamin D – 21st meta-analysis – Oct 2021		29 Oct, 2021
Colorectal cancer 25 percent less likely if good level of Vitamin D – 20th meta-analysis – June 2021		02 Jul, 2021
Lung Cancer death 40 percent less likely if high level of Vitamin D – meta-analysis Nov 2020		24 Nov, 2020
Deaths from many types of Cancer associated with low vitamin D- review of meta-analyses Sept 2020		09 Nov, 2020
Vitamin D fights 13 cancers – review of 35 meta-analyses – Oct 2020		06 Oct, 2020
Breast Cancer again associated with low vitamin D – 15th meta-analysis Sept 2020		02 Oct, 2020
Colorectal cancer treated by Vitamin D – 19th meta-analysis – Sept 2020		17 Sep, 2020
3X less risk of Liver cancer if more than 30 ng of vitamin D – meta-analysis July 2020		28 Jul, 2020
Liver Cancer 8 percent less likely for every 4 ng higher level of vitamin D – Meta-analysis April 2020		02 Apr, 2020
Breast Cancer risk reduced 17 percent by 1 hour of daily summer sun – meta-analysis Jan 2020		07 Jan, 2020
Liver Cancer – higher risk if poor genes (Vitamin D receptor etc) – meta-analysis Dec 2019		14 Dec, 2019
Colon cancer both prevented and treated by Vitamin D – meta-analysis Dec 2019		04 Dec, 2019
Risk of Cancer increased if poor Vitamin D Receptor – meta-analysis of 73 studies Jan 2016		09 Nov, 2019
Cancer with low Vitamin D increases Mortality by 13 percent – meta-analysis Feb 2019		05 Jul, 2019
People supplemented with Vitamin D had 13 percent fewer Cancer deaths – Meta-analysis of RCT June 2019		05 Jul, 2019
Breast Cancer rate reduced by 40 percent with Omega-3 – meta-analysis June 2013		16 Jun, 2019
Lung Cancer more likely if poor Vitamin D Receptor – meta-analysis June 2019		13 Jun, 2019
Variety of Vitamin D forms treat Prostate Cancer – RCT Review April 2019		01 May, 2019
Pancreatic cancer risk of death reduced 19 percent by Vitamin D – meta-analysis June 2017		20 Mar, 2019
Breast Cancer reduced 20 percent by fish (Omega-3) – meta-analysis Feb 2019		05 Mar, 2019
16 percent less Prostate Cancer sometimes for each 10 ng vitamin D increase - meta-analysis Jan 2011		13 Oct, 2018
Lung Cancer risk decreased 2.4 percent with every 100 IU Vitamin D extra intake – meta-analysis Sept 2018		15 Sep, 2018
Colorectal cancer is associated with Vitamin D (17 meta-analyses so far) – July 2018		18 Jul, 2018
Thyroid Cancer 1.3X higher risk if low vitamin D (yet again) – meta-analysis June 2018		02 Jun, 2018
Cancer not treated by Vitamin D when ignore dose size, type, and length of trial – meta-analysis April 2018		09 Apr, 2018
Pancreatic cancer risk reduced 25 percent by just 10 micrograms of Vitamin D or Vitamin B12 – meta-analysis March 2018		30 Mar, 2018
Prostate cancer risk increase with Vitamin D (other studies disagree) – meta-analysis Jan 2018		11 Jan, 2018
Lung Cancer death 60 percent less likely if high level of vitamin D – 2 meta-analysis 2017		29 Dec, 2017
Ovarian Cancer in Asia is 1.5 X more likely if poor Vitamin D receptor – meta-analysis Dec 2017		14 Dec, 2017
Lung Cancer patients were 2.4 times more likely to have a poor Vitamin D Receptor gene – July 2017		27 Jul, 2017
Lung Cancer less likely if vitamin D (higher level or supplement) – meta-analysis May 2015		06 Jul, 2017
Breast Cancer Mortality reduced 60 percent if more than 60 ng of Vitamin D – meta-analysis June 2017		13 Jun, 2017
Lung Cancer risk decreases 5 percent for every 2.5 nanogram increase in Vitamin D – meta-analysis Sept 2015		22 Feb, 2017
Colorectal cancer 60 percent less likely: high vs low Vitamin D level – meta-analysis Dec 2016		22 Dec, 2016
Colorectal Cancer recurrence not prevented by 1,000 IU of vitamin D – meta-analysis Dec 2016		09 Dec, 2016
Bladder cancer modifiable risk factors include low vitamin D – meta-analysis March 2016		08 Dec, 2016
Bladder cancer 60 percent less likely if have high vitamin D – meta-analysis Dec 2015		08 Dec, 2016
Vitamin D receptor polymorphisms are risk factors for various cancers – meta-analysis Jan 2014		12 Nov, 2016
10 percent of colon cancer linked to Vitamin D Receptor – meta-analysis April 2012		23 Sep, 2016
Kidney cancer 22 percent less likely if high vitamin D – meta-analysis Nov 2015		30 Mar, 2016
Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis April 2015		24 Dec, 2015
Bladder cancer 25 percent less likely if have high vitamin D – meta-analysis Oct 2014		24 Dec, 2015
Cancer risk weakly associated with vitamin D-binding protein – meta-analysis Sept 2015		15 Oct, 2015
Colon cancer 30 percent more likely if low vitamin D – 12th meta-analysis Aug 2015		14 Aug, 2015
Obesity causes 20 percent of all cancer, low vitamin D may be the connection – meta-analysis - Sept 2014		31 May, 2015
Increased risk of some female cancers if low vitamin D (due to genes) – meta-analysis June 2015		03 May, 2015
Colon cancer risk reduced by many vitamins – 13 percent reduction by Vitamin D – meta-analysis Jan 2015		11 Dec, 2014
Breast Cancer – review of 2 RCT did not find association with 1000 IU of Vitamin D – July 2013		16 Nov, 2014
Cancer (colon, breast, lymph) survival about 2X better with high level vitamin D – meta-analysis July 2014		30 Sep, 2014
Colorectal and Breast Cancer – Vitamin D is associated with fewer deaths – meta-analysis Feb 2014		30 Sep, 2014
Cancer survival 4 percent more likely with just a little more vitamin D (4 ng) - meta-analysis July 2014		12 May, 2014
More survive Breast Cancer if more vitamin D – 2X fewer deaths with just 30 ng -meta-analysis March 2014		08 May, 2014
Death due to breast cancer reduced 40 percent if high vitamin D – meta-analysis April 2014		08 Apr, 2014
Breast Cancer survival 2X more likely if vitamin D sufficient – meta-analysis May 2013		06 Mar, 2014
Breast Cancer post menopause down 12 percent for every 5 ng of vitamin D – meta-analysis May 2013		28 Oct, 2013
Probably need more than 1000 IU of vitamin D to prevent cancer – meta-analysis Aug 2013		20 Aug, 2013
3.2 percent less Breast Cancer for 2.4 ng more vitamin D – meta-analysis June 2013		08 Jul, 2013
Colorectal cancer 26 percent less likely for every 10 ng of vitamin D – meta-analysis Aug 2011		10 Nov, 2012
Breast cancer association with low vitamin D suggested by Meta-analysis -April 2010		19 Jul, 2012
Colon cancer probability increases with decreased vitamin D – Meta-analysis July 2011		23 Jun, 2012
Vitamin D has a complex relationship with Cancer – meta-analysis July 2011		30 Sep, 2011
Meta-analysis of 3 cancers - 10 ng more vitamin D decrease colorectal by 15 percent– May 2010		31 Aug, 2011
Risk of Prostate Cancer weakly associated with vitamin D - meta-analysis March 2011		11 Aug, 2011
Meta-analysis found vitamin D association with colon but not prostate nor breast cancer May 2010		17 Jan, 2011
Meta-analysis not find low vitamin D years before breast cancer – Aug 2010		10 Sep, 2010
Meta-analysis confirmed that vitamin D and calcium prevents breast cancer – June 2010		30 Aug, 2010
Meta-analysis did not find strong association between vitamin D and breast cancer risk -April 2010		12 May, 2010

VitaminDWiki Meta-analyses with COPD in title (6 as of June 2022)

This list is automatically updated

Items found: 6

Title		Modified
COPD treated by Vitamin D – meta-analysis March 2022		12 Mar, 2022
COPD severity is associated with Vitamin D deficiency – meta-analyses 2015, 2019		17 Mar, 2019
COPD 2.8 times more likely to be severe if low vitamin D – meta-analysis Oct 2016		13 Sep, 2018
COPD strongly associated with Vitamin D Binding Protein problems – meta-analysis Aug 2015		12 Jun, 2017
Gene makes COPD 2.6X more likely unless get more vitamin D – meta-analysis Dec 2014		04 Nov, 2015
Asthma is strongly associated with low vitamin D (but not COPD) – meta-analysis Feb 2014		17 Mar, 2014

VitaminDWiki - 44 COVID Meta-analyses

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Many chronic and acute diseases are fought by Vitamin D – June 2022

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