The worse the Periodontitis, the lower the Vitamin D – April 2022

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Vitamin D3 Serum Levels in Periodontitis Patients: A Case–Control Study

by Iwona Olszewska-Czyz 1,*ORCID andElena Firkova 2
1 Department of Periodontology, Prophylaxis and Oral Pathology, Medical Faculty, Jagiellonian University, 31155 Krakow, Poland
2 Department of Periodontology and Oral Diseases, Faculty of Dental Medicine, Medical University–Plovdiv, 4002 Plovdiv, Bulgaria
Medicina 2022, 58(5), 585; https://doi.org/10.3390/medicina58050585

Background: Periodontitis is a multifactorial disease characterized by bacterial-dysbiosis-associated, host-mediated inflammation, which results in the loss of the tooth-supporting tissues. Vitamin D3 plays an important role in the tissue homeostasis and its deficiency might have a negative effect on the periodontitis progression and treatment outcomes.

Objectives: The aim of the study was to evaluate the vitamin D3 serum levels among patients with periodontitis and healthy subjects. Materials and

Methods: A total of 100 generally healthy adult participants (50 diagnosed with periodontitis, 50 with healthy periodontium) were enrolled in the study. The periodontal clinical parameters were measured, radiographs were performed and the 25-hydroxy vitamin D (25(OH)D) test was used to assess vitamin D3 levels.

Results: Vitamin D3 levels were found to be statistically significantly lower among periodontitis patients (31.34; SD = 5.62) compared with healthy controls (39.64; SD = 8.77). Vitamin D3 deficiency was corresponding to the stage and grade of the disease as well as the clinical attachment and bone loss.

Conclusion: Adequate monitoring of the vitamin D3 serum levels and supplementation could be of benefit in periodontitis treatment.
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VitaminDWiki pages with PERIODONTITIS in title (19 as of April 2022)

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VitaminDWiki - Dental contains

116 Dental items

Some Dental studies

• Vitamin D cut dental caries in half 80 years ago – meta-analysis 2013 80 years ago
• Caries (tooth decay) and Vitamin D - 23+ studies
• Periodontitis reduced by Vitamin D - many studies
  • Periodontal Disease and Vitamin D - interview and transcript - GRH, Grant July 2023
  • Severe periodontitis is half as likely at 60 ng of vitamin D – Sept 2021
  • Vitamin D may provide the most peridontal benefits of all nutraceuticals – May 2018
• Risk of Oral Surgery reduced by Vitamin D – scoping review Nov 2021
• Some Dental Malocclusions 5X more likely if low vitamin D – June 2021
• Grinding teeth while sleeping (sleep bruxism) 6 X more likely if low vitamin D – Jan 2021
• Early tooth decay 1.9 X more likely if a poor Vitamin D receptor – July 2017
• 7 Intervention AND Dental studies
• 19 items listed in BOTH Dental and Infant or Child
• 7 listed in BOTH Dental and Vitamin D Receptor